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Luminal breast epithelial cells from wildtype and BRCA mutation carriers harbor copy number alterations commonly associated with breast cancer.
Williams MJ, Oliphant MU, Au V, Liu C, Baril C, O'Flanagan C, Lai D, Beatty S, Van Vliet M, Yiu JC, O'Connor L, Goh WL, Pollaci A, Weiner AC, Grewal D, McPherson A, Moore M, Prabhakar V, Agarwal S, Garber JE, Dillon D, Shah SP, Brugge J, Aparicio S. Williams MJ, et al. Among authors: aparicio s. bioRxiv [Preprint]. 2024 May 3:2024.05.01.591587. doi: 10.1101/2024.05.01.591587. bioRxiv. 2024. Update in: Nat Genet. 2024 Dec;56(12):2753-2762. doi: 10.1038/s41588-024-01988-0 PMID: 38746396 Free PMC article. Updated. Preprint.
Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing.
Laks E, McPherson A, Zahn H, Lai D, Steif A, Brimhall J, Biele J, Wang B, Masud T, Ting J, Grewal D, Nielsen C, Leung S, Bojilova V, Smith M, Golovko O, Poon S, Eirew P, Kabeer F, Ruiz de Algara T, Lee SR, Taghiyar MJ, Huebner C, Ngo J, Chan T, Vatrt-Watts S, Walters P, Abrar N, Chan S, Wiens M, Martin L, Scott RW, Underhill TM, Chavez E, Steidl C, Da Costa D, Ma Y, Coope RJN, Corbett R, Pleasance S, Moore R, Mungall AJ, Mar C, Cafferty F, Gelmon K, Chia S; CRUK IMAXT Grand Challenge Team; Marra MA, Hansen C, Shah SP, Aparicio S. Laks E, et al. Among authors: aparicio s. Cell. 2019 Nov 14;179(5):1207-1221.e22. doi: 10.1016/j.cell.2019.10.026. Cell. 2019. PMID: 31730858 Free PMC article.
Circulating tumour mutation detection in triple-negative breast cancer as an adjunct to tissue response assessment.
Zaikova E, Cheng BYC, Cerda V, Kong E, Lai D, Lum A, Bates C, den Brok W, Kono T, Bourque S, Chan A, Feng X, Fenton D, Gurjal A, Levasseur N, Lohrisch C, Roberts S, Shenkier T, Simmons C, Taylor S, Villa D, Miller R, Aguirre-Hernandez R, Aparicio S, Gelmon K. Zaikova E, et al. Among authors: aparicio s. NPJ Breast Cancer. 2024 Jan 5;10(1):3. doi: 10.1038/s41523-023-00607-1. NPJ Breast Cancer. 2024. PMID: 38182588 Free PMC article.
Breast Cancer.
Visvader JE, Rosen JM, Aparicio S. Visvader JE, et al. Among authors: aparicio s. Cold Spring Harb Perspect Med. 2024 Aug 1;14(8):a041729. doi: 10.1101/cshperspect.a041729. Cold Spring Harb Perspect Med. 2024. PMID: 38692741 Review.
Insights into Carvone: Fatty Acid Hydrophobic NADES for Alkane Solubilization.
Aguilar N, Benito C, Martel-Martín S, Gutiérrez A, Rozas S, Marcos PA, Bol-Arreba A, Atilhan M, Aparicio S. Aguilar N, et al. Among authors: aparicio s. Energy Fuels. 2024 Dec 5;38(24):23633-23653. doi: 10.1021/acs.energyfuels.4c03623. eCollection 2024 Dec 19. Energy Fuels. 2024. PMID: 39720702 Free PMC article.
Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER.
Lucas O, Ward S, Zaidi R, Bunkum A, Frankell AM, Moore DA, Hill MS, Liu WK, Marinelli D, Lim EL, Hessey S, Naceur-Lombardelli C, Rowan A, Purewal-Mann SK, Zhai H, Dietzen M, Ding B, Royle G, Aparicio S; TRACERx Consortium; PEACE Consortium; McGranahan N, Jamal-Hanjani M, Kanu N, Swanton C, Zaccaria S. Lucas O, et al. Among authors: aparicio s. Nat Genet. 2025 Jan;57(1):103-114. doi: 10.1038/s41588-024-01989-z. Epub 2024 Nov 29. Nat Genet. 2025. PMID: 39614124 Free PMC article.
Luminal breast epithelial cells of BRCA1 or BRCA2 mutation carriers and noncarriers harbor common breast cancer copy number alterations.
Williams MJ, Oliphant MUJ, Au V, Liu C, Baril C, O'Flanagan C, Lai D, Beatty S, Van Vliet M, Yiu JC, O'Connor L, Goh WL, Pollaci A, Weiner AC, Grewal D, McPherson A, Norton K, Moore M, Prabhakar V, Agarwal S, Garber JE, Dillon DA, Shah SP, Brugge JS, Aparicio S. Williams MJ, et al. Among authors: aparicio s. Nat Genet. 2024 Dec;56(12):2753-2762. doi: 10.1038/s41588-024-01988-0. Epub 2024 Nov 20. Nat Genet. 2024. PMID: 39567747 Free PMC article.
479 results