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Tissue distribution and retention drives efficacy of rapidly clearing VHL-based PROTACs.
Zhang D, Ma B, Dragovich PS, Ma L, Chen S, Chen EC, Ye X, Liu J, Pizzano J, Bortolon E, Chan E, Zhang X, Chen YC, Levy ES, Yauch RL, Khojasteh SC, Hop CECA. Zhang D, et al. Among authors: ma l, ma b. Commun Med (Lond). 2024 May 16;4(1):87. doi: 10.1038/s43856-024-00505-y. Commun Med (Lond). 2024. PMID: 38755248 Free PMC article.
The Importance of Tracking "Missing" Metabolites: How and Why?
Wang S, Ballard TE, Christopher LJ, Foti RS, Gu C, Khojasteh SC, Liu J, Ma S, Ma B, Obach RS, Schadt S, Zhang Z, Zhang D. Wang S, et al. Among authors: ma b, ma s. J Med Chem. 2023 Dec 14;66(23):15586-15612. doi: 10.1021/acs.jmedchem.3c01293. Epub 2023 Sep 28. J Med Chem. 2023. PMID: 37769129 Review.
Bioactivation and reactivity research advances - 2022 year in review‡.
Wang S, Argikar UA, Cheruzel L, Cho S, Crouch RD, Dhaware D, Heck CJS, Johnson KM, Kalgutkar AS, King L, Liu J, Ma B, Maw H, Miller GP, Seneviratne HK, Takahashi RH, Wei C, Khojasteh SC. Wang S, et al. Among authors: ma b. Drug Metab Rev. 2023 Nov;55(4):267-300. doi: 10.1080/03602532.2023.2244193. Epub 2023 Aug 22. Drug Metab Rev. 2023. PMID: 37608698 Review.
Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection.
Vermillion MS, Murakami E, Ma B, Pitts J, Tomkinson A, Rautiola D, Babusis D, Irshad H, Seigel D, Kim C, Zhao X, Niu C, Yang J, Gigliotti A, Kadrichu N, Bilello JP, Ellis S, Bannister R, Subramanian R, Smith B, Mackman RL, Lee WA, Kuehl PJ, Hartke J, Cihlar T, Porter DP. Vermillion MS, et al. Among authors: ma b. Sci Transl Med. 2022 Feb 23;14(633):eabl8282. doi: 10.1126/scitranslmed.abl8282. Epub 2022 Feb 23. Sci Transl Med. 2022. PMID: 34968150 Free PMC article.
6,558 results