Wen T - Search Results

1

Polysaccharides extracted from larvae of Lucilia sericata ameliorated ulcerative colitis by regulating the intestinal barrier and gut microbiota.

Wang R, Yan B, Yin Y, Wang X, Wu M, Wen T, Qian Y, Wang Y, Huang C, Zhu Y. Wang R, et al. Among authors: wen t. Int J Biol Macromol. 2024 Jun;270(Pt 2):132441. doi: 10.1016/j.ijbiomac.2024.132441. Epub 2024 May 16. Int J Biol Macromol. 2024. PMID: 38761897

2

Discovery of novel pyrimidine molecules containing boronic acid as VCP/p97 Inhibitors.

Zhang Y, Xie X, Wang X, Wen T, Zhao C, Liu H, Zhao B, Zhu Y. Zhang Y, et al. Among authors: wen t. Bioorg Med Chem. 2021 May 15;38:116114. doi: 10.1016/j.bmc.2021.116114. Epub 2021 Mar 23. Bioorg Med Chem. 2021. PMID: 33831696

3

Discovery of novel tripeptide propylene oxide proteasome inhibitors for the treatment of multiple myeloma.

Zhang W, Wang X, Zhang H, Wen T, Yang L, Miao H, Wang J, Liu H, Yang X, Lei M, Zhu Y. Zhang W, et al. Among authors: wen t. Bioorg Med Chem. 2021 Jun 15;40:116182. doi: 10.1016/j.bmc.2021.116182. Epub 2021 May 1. Bioorg Med Chem. 2021. PMID: 33971487

4

Preclinical Pharmacokinetics, Tissue Distribution and in vitro Metabolism of FHND6091, a Novel Oral Proteasome Inhibitor.

Yang X, Liu A, Yang L, Wen T, Wang J, Shi J, Zhou H, Chen Z, Lei M, Zhu Y. Yang X, et al. Among authors: wen t. Drug Des Devel Ther. 2022 Sep 13;16:3087-3107. doi: 10.2147/DDDT.S371020. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 36124108 Free PMC article.

5

Discovery of a new class of valosine containing protein (VCP/P97) inhibitors for the treatment of colorectal cancer.

Wang X, Wen T, Miao H, Hu W, Lei M, Zhu Y. Wang X, et al. Among authors: wen t. Bioorg Med Chem. 2022 Nov 15;74:117050. doi: 10.1016/j.bmc.2022.117050. Epub 2022 Oct 8. Bioorg Med Chem. 2022. PMID: 36228523

6

Co-delivery of immunochemotherapeutic by classified targeting based on chitosan and cyclodextrin derivatives.

Chen Z, Wen T, Wang X, Yang L, Wang Z, Qin Y, Hu Y, Zhang T, Wang D, Liu A, Zhang L, Lei M, Zhu Y. Chen Z, et al. Among authors: wen t. Int J Biol Macromol. 2023 Jan 31;226:1396-1410. doi: 10.1016/j.ijbiomac.2022.11.253. Epub 2022 Nov 26. Int J Biol Macromol. 2023. PMID: 36442558

7

Design and discovery of novel dipeptide boronic acid ester proteasome inhibitors, an oral slowly-released prodrug for the treatment of multiple myeloma.

Wang X, Zhang W, Wen T, Miao H, Hu W, Liu H, Lei M, Zhu Y. Wang X, et al. Among authors: wen t. Eur J Med Chem. 2023 Mar 15;250:115187. doi: 10.1016/j.ejmech.2023.115187. Epub 2023 Feb 13. Eur J Med Chem. 2023. PMID: 36806958

8

KPT-330 and Y219 exert a synergistic antitumor effect in triple-negative breast cancer through inhibiting NF-κB signaling.

Wen T, Geng M, Bai E, Wang X, Miao H, Chen Z, Zhou H, Wang J, Shi J, Zhang Y, Lei M, Zhu Y. Wen T, et al. FEBS Open Bio. 2023 Apr;13(4):751-762. doi: 10.1002/2211-5463.13588. Epub 2023 Mar 20. FEBS Open Bio. 2023. PMID: 36847599 Free PMC article.

9

Preclinical Pharmacokinetics and in vitro Metabolism of FHND5071, a Novel Selective RET Kinase Inhibitor.

Han Y, Wen T, Wang J, Shi J, Zhu Y. Han Y, et al. Among authors: wen t. Eur J Drug Metab Pharmacokinet. 2023 Sep;48(5):595-614. doi: 10.1007/s13318-023-00844-6. Epub 2023 Aug 2. Eur J Drug Metab Pharmacokinet. 2023. PMID: 37528327

10

Proteasome inhibitors FHND6091 enhance the ability of NK cells to kill tumor cells through multiple mechanisms.

Liu A, Wen T, Ding L, Qin Y, Li C, Lei M, Zhu Y. Liu A, et al. Among authors: wen t. Eur J Pharmacol. 2024 Aug 15;977:176716. doi: 10.1016/j.ejphar.2024.176716. Epub 2024 Jun 6. Eur J Pharmacol. 2024. PMID: 38849039

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