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Page 1
Frequency and spectrum of mutations in human sperm measured using duplex sequencing correlate with trio-based de novo mutation analyses.
Axelsson J, LeBlanc D, Shojaeisaadi H, Meier MJ, Fitzgerald DM, Nachmanson D, Carlson J, Golubeva A, Higgins J, Smith T, Lo FY, Pilsner R, Williams A, Salk J, Marchetti F, Yauk C. Axelsson J, et al. Among authors: nachmanson d. Sci Rep. 2024 Oct 8;14(1):23134. doi: 10.1038/s41598-024-73587-2. Sci Rep. 2024. PMID: 39379474 Free PMC article.
A genome-wide CRISPR screen reveals that antagonism of glutamine metabolism sensitizes head and neck squamous cell carcinoma to ferroptotic cell death.
Allevato MM, Trinh S, Koshizuka K, Nachmanson D, Nguyen TC, Yokoyama Y, Wu X, Andres A, Wang Z, Watrous J, Molinolo AA, Mali P, Harismendy O, Jain M, Wild R, Gutkind JS. Allevato MM, et al. Among authors: nachmanson d. Cancer Lett. 2024 Aug 28;598:217089. doi: 10.1016/j.canlet.2024.217089. Epub 2024 Jul 2. Cancer Lett. 2024. PMID: 38964731
Tumor microenvironmental determinants of high-risk DCIS progression.
Borowsky A, Glencer A, Ramalingam K, Schindler N, Mori H, Ghule P, Lee K, Nachmanson D, Officer A, Harismendy O, Stein J, Stein G, Evans M, Weaver D, Yau C, Hirst G, Campbell M, Esserman L. Borowsky A, et al. Among authors: nachmanson d. Res Sq [Preprint]. 2024 May 9:rs.3.rs-4126092. doi: 10.21203/rs.3.rs-4126092/v1. Res Sq. 2024. PMID: 38766192 Free PMC article. Preprint.
Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats.
Smith-Roe SL, Hobbs CA, Hull V, Todd Auman J, Recio L, Streicker MA, Rivas MV, Pratt GA, Lo FY, Higgins JE, Schmidt EK, Williams LN, Nachmanson D, Valentine Iii CC, Salk JJ, Witt KL. Smith-Roe SL, et al. Among authors: nachmanson d. Mutat Res Genet Toxicol Environ Mutagen. 2023 Oct;891:503669. doi: 10.1016/j.mrgentox.2023.503669. Epub 2023 Aug 3. Mutat Res Genet Toxicol Environ Mutagen. 2023. PMID: 37770135 Free PMC article.
Integrated Molecular Characterization of Intraductal Papillary Mucinous Neoplasms: An NCI Cancer Moonshot Precancer Atlas Pilot Project.
Semaan A, Bernard V, Wong J, Makino Y, Swartzlander DB, Rajapakshe KI, Lee JJ, Officer A, Schmidt CM, Wu HH, Scaife CL, Affolter KE, Nachmanson D, Firpo MA, Yip-Schneider M, Lowy AM, Harismendy O, Sen S, Maitra A, Jakubek YA, Guerrero PA. Semaan A, et al. Among authors: nachmanson d. Cancer Res Commun. 2023 Oct 10;3(10):2062-2073. doi: 10.1158/2767-9764.CRC-22-0419. Cancer Res Commun. 2023. PMID: 37721516 Free PMC article.
Adopting Duplex Sequencing™ Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)-Exposed Rats.
Smith-Roe SL, Hobbs CA, Hull V, Auman JT, Recio L, Streicker MA, Rivas MV, Pratt GA, Lo FY, Higgins JE, Schmidt EK, Williams LN, Nachmanson D, Valentine CC 3rd, Salk JJ, Witt KL. Smith-Roe SL, et al. Among authors: nachmanson d. bioRxiv [Preprint]. 2023 May 9:2023.05.08.539833. doi: 10.1101/2023.05.08.539833. bioRxiv. 2023. Update in: Mutat Res Genet Toxicol Environ Mutagen. 2023 Oct;891:503669. doi: 10.1016/j.mrgentox.2023.503669. PMID: 37214853 Free PMC article. Updated. Preprint.
The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ.
Nachmanson D, Officer A, Mori H, Gordon J, Evans MF, Steward J, Yao H, O'Keefe T, Hasteh F, Stein GS, Jepsen K, Weaver DL, Hirst GL, Sprague BL, Esserman LJ, Borowsky AD, Stein JL, Harismendy O. Nachmanson D, et al. NPJ Breast Cancer. 2022 Jan 13;8(1):6. doi: 10.1038/s41523-021-00365-y. NPJ Breast Cancer. 2022. PMID: 35027560 Free PMC article.
PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage.
Zhang Y, Kohrn BF, Yang M, Nachmanson D, Soong TR, Lee IH, Tao Y, Clevers H, Swisher EM, Brentnall TA, Loeb LA, Kennedy SR, Salk JJ, Naxerova K, Risques RA. Zhang Y, et al. Among authors: nachmanson d. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2023373118. doi: 10.1073/pnas.2023373118. Proc Natl Acad Sci U S A. 2021. PMID: 34330826 Free PMC article.
18 results