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Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nguyen BA, Singh V, Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P, Pękała M, Cabrera Hernandez LO, Kumar S, Lemoff A, Gonzalez-Prieto R, Sawaya MR, Eisenberg DS, Benson MD, Saelices L. Nguyen BA, et al. Among authors: ahmed y. Nat Commun. 2024 Jan 17;15(1):581. doi: 10.1038/s41467-024-44820-3. Nat Commun. 2024. PMID: 38233397 Free PMC article.
Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis.
Nguyen BA, Singh V, Afrin S, Singh P, Pekala M, Ahmed Y, Pedretti R, Canepa J, Lemoff A, Kluve-Beckerman B, Wydorski P, Chhapra F, Saelices L. Nguyen BA, et al. Among authors: ahmed y. bioRxiv [Preprint]. 2024 Mar 9:2024.03.08.582936. doi: 10.1101/2024.03.08.582936. bioRxiv. 2024. Update in: Commun Biol. 2024 Jul 27;7(1):905. doi: 10.1038/s42003-024-06588-6. PMID: 38496656 Free PMC article. Updated. Preprint.
ATTRv-V30M Type A amyloid fibrils from heart and nerves exhibit structural homogeneity.
Nguyen BA, Afrin S, Yakubovska A, Singh V, Alicea JV, Kunach P, Singh P, Pekala M, Ahmed Y, Fernandez-Ramirez MDC, Hernandez LOC, Pedretti R, Bassett P, Wang L, Lemoff A, Villalon L, Kluve-Beckerman B, Saelices L. Nguyen BA, et al. Among authors: ahmed y. bioRxiv [Preprint]. 2024 May 14:2024.05.14.594028. doi: 10.1101/2024.05.14.594028. bioRxiv. 2024. Update in: Structure. 2024 Oct 9:S0969-2126(24)00421-0. doi: 10.1016/j.str.2024.09.021. PMID: 38798361 Free PMC article. Updated. Preprint.
777 results