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Linear ubiquitin chains remodel the proteome and influence the levels of hundreds of regulators in Drosophila.
Nuga O, Richardson K, Patel N, Wang X, Pagala V, Stephan A, Peng J, Demontis F, Todi SV. Nuga O, et al. Among authors: peng j. bioRxiv [Preprint]. 2024 May 10:2024.05.09.593206. doi: 10.1101/2024.05.09.593206. bioRxiv. 2024. Update in: G3 (Bethesda). 2024 Nov 6;14(11):jkae209. doi: 10.1093/g3journal/jkae209 PMID: 38766269 Free PMC article. Updated. Preprint.
Phosphorylation of 53BP1 by ATM enforce neurodevelopmental programs in cortical organoids.
Lim B, Djekidel MN, Matsui Y, Jung S, Yuan ZF, Wang X, Yang X, Pilehroud AS, Pan H, Wang F, Pruett-Miller S, Kavdia K, Pagala V, Fan Y, Peng J, Xu B, Peng JC. Lim B, et al. Among authors: peng j, peng jc. bioRxiv [Preprint]. 2023 May 4:2023.05.04.539457. doi: 10.1101/2023.05.04.539457. bioRxiv. 2023. Update in: PLoS Biol. 2024 Sep 3;22(9):e3002760. doi: 10.1371/journal.pbio.3002760 PMID: 37205560 Free PMC article. Updated. Preprint.
Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor.
Jablonowski C, Quarni W, Singh S, Tan H, Bostanthirige DH, Jin H, Fang J, Chang TC, Finkelstein D, Cho JH, Hu D, Pagala V, Sakurada SM, Pruett-Miller SM, Wang R, Murphy A, Freeman K, Peng J, Davidoff AM, Wu G, Yang J. Jablonowski C, et al. Among authors: peng j. bioRxiv [Preprint]. 2023 Nov 20:2023.06.26.546606. doi: 10.1101/2023.06.26.546606. bioRxiv. 2023. Update in: Elife. 2024 Mar 15;12:RP90993. doi: 10.7554/eLife.90993 PMID: 37425900 Free PMC article. Updated. Preprint.
Human-mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome.
Yarbro JM, Han X, Dasgupta A, Yang K, Liu D, Shrestha HK, Zaman M, Wang Z, Yu K, Lee DG, Vanderwall D, Niu M, Sun H, Xie B, Chen PC, Jiao Y, Zhang X, Wu Z, Fu Y, Li Y, Yuan ZF, Wang X, Poudel S, Vagnerova B, He Q, Tang A, Ronaldson PT, Chang R, Yu G, Liu Y, Peng J. Yarbro JM, et al. Among authors: peng j. bioRxiv [Preprint]. 2024 Oct 25:2024.10.25.620263. doi: 10.1101/2024.10.25.620263. bioRxiv. 2024. PMID: 39484428 Free PMC article. Preprint.
Longitudinal multi-omics reveals pathogenic TSC2 variants disrupt developmental trajectories of human cortical organoids derived from Tuberous Sclerosis Complex.
Niu W, Yu S, Li X, Wang Z, Chen R, Michalski C, Jahangiri A, Zohdy Y, Chern JJ, Whitworth TJ, Wang J, Xu J, Zhou Y, Qin Z, Li B, Gambello MJ, Peng J, Wen Z. Niu W, et al. Among authors: peng j. bioRxiv [Preprint]. 2024 Oct 11:2024.10.07.617121. doi: 10.1101/2024.10.07.617121. bioRxiv. 2024. PMID: 39416123 Free PMC article. Preprint.
An atypical E3 ligase safeguards the ribosome during nutrient stress.
Douglas T, Zhang J, Wu Z, Abdallah K, McReynolds M, Gilbert WV, Iwai K, Peng J, Young LH, Crews CM. Douglas T, et al. Among authors: peng j. bioRxiv [Preprint]. 2024 Oct 17:2024.10.10.617692. doi: 10.1101/2024.10.10.617692. bioRxiv. 2024. PMID: 39416039 Free PMC article. Preprint.
Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia.
Bergeron BP, Barnett KR, Bhattarai KR, Mobley RJ, Hansen BS, Brown A, Kodali K, High AA, Jeha S, Pui CH, Peng J, Pruett-Miller SM, Savic D. Bergeron BP, et al. Among authors: peng j. bioRxiv [Preprint]. 2023 May 13:2023.01.20.524798. doi: 10.1101/2023.01.20.524798. bioRxiv. 2023. Update in: Blood Adv. 2023 Aug 8;7(15):4107-4111. doi: 10.1182/bloodadvances.2022009498 PMID: 36711662 Free PMC article. Updated. Preprint.
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