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Predictive gene expression signature diagnoses neonatal sepsis before clinical presentation.
An AY, Acton E, Idoko OT, Shannon CP, Blimkie TM, Falsafi R, Wariri O, Imam A, Dibbasey T, Bennike TB, Smolen KK, Diray-Arce J, Ben-Othman R, Montante S, Angelidou A, Odumade OA, Martino D, Tebbutt SJ, Levy O, Steen H, Kollmann TR, Kampmann B, Hancock REW, Lee AH; EPIC Consortium. An AY, et al. EBioMedicine. 2024 Dec;110:105411. doi: 10.1016/j.ebiom.2024.105411. Epub 2024 Oct 28. EBioMedicine. 2024. PMID: 39472236 Free PMC article.
Angiogenesis-associated pathways play critical roles in neonatal sepsis outcomes.
Fidanza M, Hibbert J, Acton E, Harbeson D, Schoeman E, Skut P, Woodman T, Eynaud A, Hartnell L, Brook B, Cai B, Lo M, Falsafi R, Hancock REW, Chiume-Kayuni M, Lufesi N, Popescu CR, Lavoie PM, Strunk T, Currie AJ, Kollmann TR, Amenyogbe N, Lee AH. Fidanza M, et al. Among authors: harbeson d. Sci Rep. 2024 May 20;14(1):11444. doi: 10.1038/s41598-024-62195-9. Sci Rep. 2024. PMID: 38769383 Free PMC article.
BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis.
Brook B, Harbeson DJ, Shannon CP, Cai B, He D, Ben-Othman R, Francis F, Huang J, Varankovich N, Liu A, Bao W, Bjerregaard-Andersen M, Schaltz-Buchholzer F, Sanca L, Golding CN, Larsen KL, Levy O, Kampmann B; EPIC Consortium; Tan R, Charles A, Wynn JL, Shann F, Aaby P, Benn CS, Tebbutt SJ, Kollmann TR, Amenyogbe N. Brook B, et al. Among authors: harbeson dj. Sci Transl Med. 2020 May 6;12(542):eaax4517. doi: 10.1126/scitranslmed.aax4517. Sci Transl Med. 2020. PMID: 32376769 Free PMC article.
Dynamic molecular changes during the first week of human life follow a robust developmental trajectory.
Lee AH, Shannon CP, Amenyogbe N, Bennike TB, Diray-Arce J, Idoko OT, Gill EE, Ben-Othman R, Pomat WS, van Haren SD, Cao KL, Cox M, Darboe A, Falsafi R, Ferrari D, Harbeson DJ, He D, Bing C, Hinshaw SJ, Ndure J, Njie-Jobe J, Pettengill MA, Richmond PC, Ford R, Saleu G, Masiria G, Matlam JP, Kirarock W, Roberts E, Malek M, Sanchez-Schmitz G, Singh A, Angelidou A, Smolen KK; EPIC Consortium; Brinkman RR, Ozonoff A, Hancock REW, van den Biggelaar AHJ, Steen H, Tebbutt SJ, Kampmann B, Levy O, Kollmann TR. Lee AH, et al. Among authors: harbeson dj. Nat Commun. 2019 Mar 12;10(1):1092. doi: 10.1038/s41467-019-08794-x. Nat Commun. 2019. PMID: 30862783 Free PMC article.
A Controlled Mouse Model for Neonatal Polymicrobial Sepsis.
Brook B, Amenyogbe N, Ben-Othman R, Cai B, Harbeson D, Francis F, Liu AC, Varankovich N, Wynn J, Kollmann TR. Brook B, et al. Among authors: harbeson d. J Vis Exp. 2019 Jan 27;(143). doi: 10.3791/58574. J Vis Exp. 2019. PMID: 30741260
Probiotic Studies in Neonatal Mice Using Gavage.
Francis F, Varankovich N, Brook B, Amenyogbe N, Ben-Othman R, Cai B, Harbeson D, Liu AC, Dai B, McErlane S, Andrews K, Kollmann TR, Panigrahi P. Francis F, et al. Among authors: harbeson d. J Vis Exp. 2019 Jan 27;(143). doi: 10.3791/59074. J Vis Exp. 2019. PMID: 30741256