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JNJ-7184, a respiratory syncytial virus inhibitor targeting the connector domain of the viral polymerase.
Bonneux B, Shareef A, Tcherniuk S, Anson B, de Bruyn S, Verheyen N, Thys K, Conceição-Neto N, Van Ginderen M, Kwanten L, Ysebaert N, Vranckx L, Peeters E, Lanckacker E, Gallup JM, Sitthicharoenchai P, Alnajjar S, Ackermann MR, Adhikary S, Bhaumik A, Patrick A, Fung A, Sutto-Ortiz P, Decroly E, Mason SW, Lançois D, Deval J, Jin Z, Eléouët JF, Fearns R, Koul A, Roymans D, Rigaux P, Herschke F. Bonneux B, et al. Among authors: thys k. Antiviral Res. 2024 Jul;227:105907. doi: 10.1016/j.antiviral.2024.105907. Epub 2024 May 19. Antiviral Res. 2024. PMID: 38772503 Free article.
High-throughput analysis of human cytomegalovirus genome diversity highlights the widespread occurrence of gene-disrupting mutations and pervasive recombination.
Sijmons S, Thys K, Mbong Ngwese M, Van Damme E, Dvorak J, Van Loock M, Li G, Tachezy R, Busson L, Aerssens J, Van Ranst M, Maes P. Sijmons S, et al. Among authors: thys k. J Virol. 2015 Aug 1;89(15):7673-7695. doi: 10.1128/JVI.00578-15. Epub 2015 May 13. J Virol. 2015. PMID: 25972543 Free PMC article.
Adenoviral vectors expressing siRNAs for discovery and validation of gene function.
Arts GJ, Langemeijer E, Tissingh R, Ma L, Pavliska H, Dokic K, Dooijes R, Mesić E, Clasen R, Michiels F, van der Schueren J, Lambrecht M, Herman S, Brys R, Thys K, Hoffmann M, Tomme P, van Es H. Arts GJ, et al. Among authors: thys k. Genome Res. 2003 Oct;13(10):2325-32. doi: 10.1101/gr.1332603. Epub 2003 Sep 15. Genome Res. 2003. PMID: 12975310 Free PMC article.
Acquired resistance of Mycobacterium tuberculosis to bedaquiline.
Andries K, Villellas C, Coeck N, Thys K, Gevers T, Vranckx L, Lounis N, de Jong BC, Koul A. Andries K, et al. Among authors: thys k. PLoS One. 2014 Jul 10;9(7):e102135. doi: 10.1371/journal.pone.0102135. eCollection 2014. PLoS One. 2014. PMID: 25010492 Free PMC article.
Serum and mucosal antibody-mediated protection and identification of asymptomatic respiratory syncytial virus infection in community-dwelling older adults in Europe.
Öner D, Vernhes C, Balla-Jhagjhoorsingh S, Moureau A, Crabbe M, Salaun B, Bastian AR, Thys K, De Smedt J, Ooft SN, Korsten K, Adriaenssens N, Coenen S, Butler CC, Verheij TJM, Drysdale SB, Wildenbeest JG, Pollard AJ, Openshaw PJM, Bont L, Aerssens J. Öner D, et al. Among authors: thys k. Front Immunol. 2024 Oct 18;15:1448578. doi: 10.3389/fimmu.2024.1448578. eCollection 2024. Front Immunol. 2024. PMID: 39493753 Free PMC article.
A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Kaptein SJF, Goethals O, Kiemel D, Marchand A, Kesteleyn B, Bonfanti JF, Bardiot D, Stoops B, Jonckers THM, Dallmeier K, Geluykens P, Thys K, Crabbe M, Chatel-Chaix L, Münster M, Querat G, Touret F, de Lamballerie X, Raboisson P, Simmen K, Chaltin P, Bartenschlager R, Van Loock M, Neyts J. Kaptein SJF, et al. Among authors: thys k. Nature. 2021 Oct;598(7881):504-509. doi: 10.1038/s41586-021-03990-6. Epub 2021 Oct 6. Nature. 2021. PMID: 34616043
45 results