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Page 1
Pyridopyrimidinone inhibitors of HIV-1 RNase H.
Velthuisen EJ, Johns BA, Gerondelis P, Chen Y, Li M, Mou K, Zhang W, Seal JW, Hightower KE, Miranda SR, Brown K, Leesnitzer L. Velthuisen EJ, et al. Eur J Med Chem. 2014 Aug 18;83:609-16. doi: 10.1016/j.ejmech.2014.06.061. Epub 2014 Jun 28. Eur J Med Chem. 2014. PMID: 24997293
Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase.
Gupta K, Turkki V, Sherrill-Mix S, Hwang Y, Eilers G, Taylor L, McDanal C, Wang P, Temelkoff D, Nolte RT, Velthuisen E, Jeffrey J, Van Duyne GD, Bushman FD. Gupta K, et al. Among authors: velthuisen e. PLoS Biol. 2016 Dec 9;14(12):e1002584. doi: 10.1371/journal.pbio.1002584. eCollection 2016 Dec. PLoS Biol. 2016. PMID: 27935939 Free PMC article.
Allosteric inhibition of human immunodeficiency virus integrase: late block during viral replication and abnormal multimerization involving specific protein domains.
Gupta K, Brady T, Dyer BM, Malani N, Hwang Y, Male F, Nolte RT, Wang L, Velthuisen E, Jeffrey J, Van Duyne GD, Bushman FD. Gupta K, et al. Among authors: velthuisen e. J Biol Chem. 2014 Jul 25;289(30):20477-88. doi: 10.1074/jbc.M114.551119. J Biol Chem. 2014. PMID: 24904063 Free PMC article.