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Page 1
Blood methylation biomarkers are associated with diabetic kidney disease progression in type 1 diabetes.
Syreeni A, Dahlström EH, Smyth LJ, Hill C, Mutter S, Gupta Y, Harjutsalo V, Chen Z, Natarajan R, Krolewski AS, Hirschhorn JN, Florez JC; GENIE consortium; Maxwell AP, Groop PH, McKnight AJ, Sandholm N. Syreeni A, et al. medRxiv [Preprint]. 2024 Nov 29:2024.11.28.24318055. doi: 10.1101/2024.11.28.24318055. medRxiv. 2024. PMID: 39649605 Free PMC article. Preprint.
Whole-exome and whole-genome sequencing of 1064 individuals with type 1 diabetes reveals novel genes for diabetic kidney disease.
Haukka JK, Antikainen AA, Valo E, Syreeni A, Dahlström EH, Lin BM, Franceschini N, Krolewski AS, Harjutsalo V, Groop PH, Sandholm N; FinnDiane Study Group. Haukka JK, et al. Among authors: syreeni a. Diabetologia. 2024 Nov;67(11):2494-2506. doi: 10.1007/s00125-024-06241-1. Epub 2024 Aug 6. Diabetologia. 2024. PMID: 39103720 Free PMC article.
Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes.
Antikainen AA, Haukka JK, Kumar A, Syreeni A, Hägg-Holmberg S, Ylinen A, Kilpeläinen E, Kytölä A, Palotie A, Putaala J, Thorn LM, Harjutsalo V, Groop PH, Sandholm N; FinnDiane Study Group. Antikainen AA, et al. Among authors: syreeni a. Sci Rep. 2024 Jun 11;14(1):13453. doi: 10.1038/s41598-024-61840-7. Sci Rep. 2024. PMID: 38862513 Free PMC article.
Integrated analysis of blood DNA methylation, genetic variants, circulating proteins, microRNAs, and kidney failure in type 1 diabetes.
Chen Z, Satake E, Pezzolesi MG, Md Dom ZI, Stucki D, Kobayashi H, Syreeni A, Johnson AT, Wu X, Dahlström EH, King JB, Groop PH, Rich SS, Sandholm N, Krolewski AS, Natarajan R. Chen Z, et al. Among authors: syreeni a. Sci Transl Med. 2024 May 22;16(748):eadj3385. doi: 10.1126/scitranslmed.adj3385. Epub 2024 May 22. Sci Transl Med. 2024. PMID: 38776390
Residual insulin secretion in individuals with type 1 diabetes in Finland: longitudinal and cross-sectional analyses.
Harsunen M, Haukka J, Harjutsalo V, Mars N, Syreeni A, Härkönen T, Käräjämäki A, Ilonen J, Knip M, Sandholm N, Miettinen PJ, Groop PH, Tuomi T. Harsunen M, et al. Among authors: syreeni a. Lancet Diabetes Endocrinol. 2023 Jul;11(7):465-473. doi: 10.1016/S2213-8587(23)00123-7. Epub 2023 Jun 5. Lancet Diabetes Endocrinol. 2023. PMID: 37290465
Reduced methylation correlates with diabetic nephropathy risk in type 1 diabetes.
Khurana I, Kaipananickal H, Maxwell S, Birkelund S, Syreeni A, Forsblom C, Okabe J, Ziemann M, Kaspi A, Rafehi H, Jørgensen A, Al-Hasani K, Thomas MC, Jiang G, Luk AO, Lee HM, Huang Y, Thewjitcharoen Y, Nakasatien S, Himathongkam T, Fogarty C, Njeim R, Eid A, Hansen TW, Tofte N, Ottesen EC, Ma RC, Chan JC, Cooper ME, Rossing P, Groop PH, El-Osta A. Khurana I, et al. Among authors: syreeni a. J Clin Invest. 2023 Feb 15;133(4):e160959. doi: 10.1172/JCI160959. J Clin Invest. 2023. PMID: 36633903 Free PMC article.
Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease.
Smyth LJ, Dahlström EH, Syreeni A, Kerr K, Kilner J, Doyle R, Brennan E, Nair V, Fermin D, Nelson RG, Looker HC, Wooster C, Andrews D, Anderson K, McKay GJ, Cole JB, Salem RM, Conlon PJ, Kretzler M, Hirschhorn JN, Sadlier D, Godson C, Florez JC; GENIE consortium; Forsblom C, Maxwell AP, Groop PH, Sandholm N, McKnight AJ. Smyth LJ, et al. Among authors: syreeni a. Nat Commun. 2022 Dec 22;13(1):7891. doi: 10.1038/s41467-022-34963-6. Nat Commun. 2022. PMID: 36550108 Free PMC article.
Whole-exome sequencing identifies novel protein-altering variants associated with serum apolipoprotein and lipid concentrations.
Sandholm N, Hotakainen R, Haukka JK, Jansson Sigfrids F, Dahlström EH, Antikainen AA, Valo E, Syreeni A, Kilpeläinen E, Kytölä A, Palotie A, Harjutsalo V, Forsblom C, Groop PH; FinnDiane Study Group. Sandholm N, et al. Among authors: syreeni a. Genome Med. 2022 Nov 23;14(1):132. doi: 10.1186/s13073-022-01135-6. Genome Med. 2022. PMID: 36419110 Free PMC article.
26 results