Lei X - Search Results

1

Discovery of novel small molecules targeting the USP21/JAK2/STAT3 axis for the treatment of triple-negative breast cancer.

Long L, Xu J, Qi X, Pen Y, Wang C, Jiang W, Peng X, Hu Z, Yi W, Xie L, Lei X, Wang Z, Zhuo L. Long L, et al. Among authors: lei x. Eur J Med Chem. 2024 Jul 5;273:116500. doi: 10.1016/j.ejmech.2024.116500. Epub 2024 May 16. Eur J Med Chem. 2024. PMID: 38776807

2

Design, synthesis and biological evaluation of N-anthraniloyl tryptamine derivatives as pleiotropic molecules for the therapy of malignant glioma.

Fan X, Li J, Long L, Shi T, Liu D, Tan W, Zhang H, Wu X, Lei X, Wang Z. Fan X, et al. Among authors: lei x. Eur J Med Chem. 2021 Oct 15;222:113564. doi: 10.1016/j.ejmech.2021.113564. Epub 2021 May 29. Eur J Med Chem. 2021. PMID: 34091208

3

pH regulators and their inhibitors in tumor microenvironment.

Liao S, Wu G, Xie Z, Lei X, Yang X, Huang S, Deng X, Wang Z, Tang G. Liao S, et al. Among authors: lei x. Eur J Med Chem. 2024 Mar 5;267:116170. doi: 10.1016/j.ejmech.2024.116170. Epub 2024 Feb 1. Eur J Med Chem. 2024. PMID: 38308950 Review.

4

Potential therapeutic targets of the JAK2/STAT3 signaling pathway in triple-negative breast cancer.

Long L, Fei X, Chen L, Yao L, Lei X. Long L, et al. Among authors: lei x. Front Oncol. 2024 Apr 18;14:1381251. doi: 10.3389/fonc.2024.1381251. eCollection 2024. Front Oncol. 2024. PMID: 38699644 Free PMC article. Review.

5

A Smart CA IX-Targeting and pH-Responsive Nano-Mixed Micelles for Delivery of FB15 with Superior Anti-Breast Cancer Efficacy.

Liu X, Zhao J, Liu F, Xie Z, Lei X, Wang Z, Yang Z, Zhou Y, Tang G. Liu X, et al. Among authors: lei x. Int J Nanomedicine. 2024 Oct 9;19:10247-10262. doi: 10.2147/IJN.S459047. eCollection 2024. Int J Nanomedicine. 2024. PMID: 39403708 Free PMC article.

6

Therapeutic activity of DCC-2036, a novel tyrosine kinase inhibitor, against triple-negative breast cancer patient-derived xenografts by targeting AXL/MET.

Shen Y, Zhang W, Liu J, He J, Cao R, Chen X, Peng X, Xu H, Zhao Q, Zhong J, Ding W, Lei X, Jiang Y, Zu X. Shen Y, et al. Among authors: lei x. Int J Cancer. 2019 Feb 1;144(3):651-664. doi: 10.1002/ijc.31915. Epub 2018 Nov 7. Int J Cancer. 2019. PMID: 30289981

7

Synthesis and anti-hepatocellular carcinoma evaluation of salicylic acid-modified indole trimethoxy flavonoid derivatives.

Zou Y, Lu N, Yang X, Xie Z, Lei X, Liu X, Li Y, Huang S, Tang G, Wang Z. Zou Y, et al. Among authors: lei x. RSC Med Chem. 2023 Apr 26;14(6):1172-1185. doi: 10.1039/d3md00128h. eCollection 2023 Jun 22. RSC Med Chem. 2023. PMID: 37360398 Free PMC article.

8

Research and development of N,N'-diarylureas as anti-tumor agents.

Sun X, Xie Z, Lei X, Huang S, Tang G, Wang Z. Sun X, et al. Among authors: lei x. RSC Med Chem. 2023 May 9;14(7):1209-1226. doi: 10.1039/d3md00053b. eCollection 2023 Jul 20. RSC Med Chem. 2023. PMID: 37484562 Free PMC article. Review.

9

The Progress of Small Molecule Targeting BCR-ABL in the Treatment of Chronic Myeloid Leukemia.

Zhang Y, Wu X, Sun X, Yang J, Liu C, Tang G, Lei X, Huang H, Peng J. Zhang Y, et al. Among authors: lei x. Mini Rev Med Chem. 2024;24(6):642-663. doi: 10.2174/0113895575218335230926070130. Mini Rev Med Chem. 2024. PMID: 37855278 Review.

10

Efficacy of Chemoimmunotherapy versus Chemotherapy for Gastric Cancer: A Meta-Analysis of Survival Outcomes.

Xie J, Chen L, Liu Q, Li XT, Lei XY. Xie J, et al. Curr Med Chem. 2024;31(18):2649-2660. doi: 10.2174/0109298673263335231121103807. Curr Med Chem. 2024. PMID: 38265394

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