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Brain cell-type shifts in Alzheimer's disease, autism, and schizophrenia interrogated using methylomics and genetics.
Yap CX, Vo DD, Heffel MG, Bhattacharya A, Wen C, Yang Y, Kemper KE, Zeng J, Zheng Z, Zhu Z, Hannon E, Vellame DS, Franklin A, Caggiano C, Wamsley B, Geschwind DH, Zaitlen N, Gusev A, Pasaniuc B, Mill J, Luo C, Gandal MJ. Yap CX, et al. Among authors: luo c. Sci Adv. 2024 May 24;10(21):eadn7655. doi: 10.1126/sciadv.adn7655. Epub 2024 May 23. Sci Adv. 2024. PMID: 38781333 Free PMC article.
Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD.
Gandal MJ, Haney JR, Wamsley B, Yap CX, Parhami S, Emani PS, Chang N, Chen GT, Hoftman GD, de Alba D, Ramaswami G, Hartl CL, Bhattacharya A, Luo C, Jin T, Wang D, Kawaguchi R, Quintero D, Ou J, Wu YE, Parikshak NN, Swarup V, Belgard TG, Gerstein M, Pasaniuc B, Geschwind DH. Gandal MJ, et al. Among authors: luo c. Nature. 2022 Nov;611(7936):532-539. doi: 10.1038/s41586-022-05377-7. Epub 2022 Nov 2. Nature. 2022. PMID: 36323788 Free PMC article.
Temporally distinct 3D multi-omic dynamics in the developing human brain.
Heffel MG, Zhou J, Zhang Y, Lee DS, Hou K, Pastor-Alonso O, Abuhanna KD, Galasso J, Kern C, Tai CY, Garcia-Padilla C, Nafisi M, Zhou Y, Schmitt AD, Li T, Haeussler M, Wick B, Zhang MJ, Xie F, Ziffra RS, Mukamel EA, Eskin E, Nowakowski TJ, Dixon JR, Pasaniuc B, Ecker JR, Zhu Q, Bintu B, Paredes MF, Luo C. Heffel MG, et al. Among authors: luo c. Nature. 2024 Nov;635(8038):481-489. doi: 10.1038/s41586-024-08030-7. Epub 2024 Oct 9. Nature. 2024. PMID: 39385032 Free PMC article.
Single-cell DNA methylome and 3D genome atlas of the human subcutaneous adipose tissue.
Chen ZJ, Das SS, Kar A, Lee SHT, Abuhanna KD, Alvarez M, Sukhatme MG, Gelev KZ, Heffel MG, Zhang Y, Avram O, Rahmani E, Sankararaman S, Heinonen S, Peltoniemi H, Halperin E, Pietiläinen KH, Luo C, Pajukanta P. Chen ZJ, et al. Among authors: luo c. bioRxiv [Preprint]. 2024 Nov 3:2024.11.02.621694. doi: 10.1101/2024.11.02.621694. bioRxiv. 2024. PMID: 39554055 Free PMC article. Preprint.
DNA methylation atlas of the mouse brain at single-cell resolution.
Liu H, Zhou J, Tian W, Luo C, Bartlett A, Aldridge A, Lucero J, Osteen JK, Nery JR, Chen H, Rivkin A, Castanon RG, Clock B, Li YE, Hou X, Poirion OB, Preissl S, Pinto-Duarte A, O'Connor C, Boggeman L, Fitzpatrick C, Nunn M, Mukamel EA, Zhang Z, Callaway EM, Ren B, Dixon JR, Behrens MM, Ecker JR. Liu H, et al. Among authors: luo c. Nature. 2021 Oct;598(7879):120-128. doi: 10.1038/s41586-020-03182-8. Epub 2021 Oct 6. Nature. 2021. PMID: 34616061 Free PMC article.
Single-cell DNA Methylome and 3D Multi-omic Atlas of the Adult Mouse Brain.
Liu H, Zeng Q, Zhou J, Bartlett A, Wang BA, Berube P, Tian W, Kenworthy M, Altshul J, Nery JR, Chen H, Castanon RG, Zu S, Li YE, Lucero J, Osteen JK, Pinto-Duarte A, Lee J, Rink J, Cho S, Emerson N, Nunn M, O'Connor C, Yao Z, Smith KA, Tasic B, Zeng H, Luo C, Dixon JR, Ren B, Behrens MM, Ecker JR. Liu H, et al. Among authors: luo c. bioRxiv [Preprint]. 2023 Apr 18:2023.04.16.536509. doi: 10.1101/2023.04.16.536509. bioRxiv. 2023. Update in: Nature. 2023 Dec;624(7991):366-377. doi: 10.1038/s41586-023-06805-y PMID: 37131654 Free PMC article. Updated. Preprint.
Single-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain.
Liu H, Zeng Q, Zhou J, Bartlett A, Wang BA, Berube P, Tian W, Kenworthy M, Altshul J, Nery JR, Chen H, Castanon RG, Zu S, Li YE, Lucero J, Osteen JK, Pinto-Duarte A, Lee J, Rink J, Cho S, Emerson N, Nunn M, O'Connor C, Wu Z, Stoica I, Yao Z, Smith KA, Tasic B, Luo C, Dixon JR, Zeng H, Ren B, Behrens MM, Ecker JR. Liu H, et al. Among authors: luo c. Nature. 2023 Dec;624(7991):366-377. doi: 10.1038/s41586-023-06805-y. Epub 2023 Dec 13. Nature. 2023. PMID: 38092913 Free PMC article.
8,544 results