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An update on late-stage functionalization in today's drug discovery.
Montgomery AP, Joyce JM, Danon JJ, Kassiou M. Montgomery AP, et al. Among authors: kassiou m. Expert Opin Drug Discov. 2023 Jun;18(6):597-613. doi: 10.1080/17460441.2023.2205635. Epub 2023 Apr 28. Expert Opin Drug Discov. 2023. PMID: 37114995 Review.
Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia.
Carey-Smith SL, Simad MH, Panchal K, Aya-Bonilla C, Smolders H, Lin S, Armitage JD, Nguyen VT, Bentley K, Ford J, Singh S, Oommen J, Laurent AP, Mercher T, Crispino JD, Montgomery AP, Kassiou M, Besson T, Deau E, Meijer L, Cheung LC, Kotecha RS, Malinge S. Carey-Smith SL, et al. Among authors: kassiou m. Haematologica. 2024 Jul 1;109(7):2309-2315. doi: 10.3324/haematol.2023.284271. Haematologica. 2024. PMID: 38426275 Free PMC article. No abstract available.
Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA.
Alzghool OM, Aarnio R, Helin JS, Wahlroos S, Keller T, Matilainen M, Solis J, Danon JJ, Kassiou M, Snellman A, Solin O, Rinne JO, Haaparanta-Solin M. Alzghool OM, et al. Among authors: kassiou m. EJNMMI Res. 2024 Mar 6;14(1):25. doi: 10.1186/s13550-024-01085-7. EJNMMI Res. 2024. PMID: 38446249 Free PMC article.
Correction: Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA.
Alzghool OM, Aarnio R, Helin JS, Wahlroos S, Keller T, Matilainen M, Solis J, Danon JJ, Kassiou M, Snellman A, Solin O, Rinne JO, Haaparanta-Solin M. Alzghool OM, et al. Among authors: kassiou m. EJNMMI Res. 2024 May 3;14(1):44. doi: 10.1186/s13550-024-01103-8. EJNMMI Res. 2024. PMID: 38700617 Free PMC article. No abstract available.
Enhancing CNS mitophagy: drug development and disease-relevant models.
Dhar KS, Townsend B, Montgomery AP, Danon JJ, Pagan JK, Kassiou M. Dhar KS, et al. Among authors: kassiou m. Trends Pharmacol Sci. 2024 Nov;45(11):982-996. doi: 10.1016/j.tips.2024.09.002. Epub 2024 Oct 16. Trends Pharmacol Sci. 2024. PMID: 39419743 Review.
261 results