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Page 1
Lung Transplant Immunomodulation with Genetically Engineered Mesenchymal Stromal Cells-Therapeutic Window for Interleukin-10.
Nykänen AI, Mariscal A, Duong A, Ali A, Takahagi A, Bai X, Zehong G, Joe B, Takahashi M, Chen M, Gokhale H, Shan H, Hwang DM, Estrada C, Yeung J, Waddell T, Martinu T, Juvet S, Cypel M, Liu M, Davies JE, Keshavjee S. Nykänen AI, et al. Among authors: gokhale h. Cells. 2024 May 17;13(10):859. doi: 10.3390/cells13100859. Cells. 2024. PMID: 38786082 Free PMC article.
Engineered mesenchymal stromal cell therapy during human lung ex vivo lung perfusion is compromised by acidic lung microenvironment.
Nykänen AI, Mariscal A, Duong A, Estrada C, Ali A, Hough O, Sage A, Chao BT, Chen M, Gokhale H, Shan H, Bai X, Zehong G, Yeung J, Waddell T, Martinu T, Juvet S, Cypel M, Liu M, Davies JE, Keshavjee S. Nykänen AI, et al. Among authors: gokhale h. Mol Ther Methods Clin Dev. 2021 Sep 20;23:184-197. doi: 10.1016/j.omtm.2021.05.018. eCollection 2021 Dec 10. Mol Ther Methods Clin Dev. 2021. PMID: 34703841 Free PMC article.
An extracellular oxygen carrier during prolonged pulmonary preservation improves post-transplant lung function.
Ali A, Watanabe Y, Galasso M, Watanabe T, Chen M, Fan E, Brochard L, Ramadan K, Ribeiro RVP, Stansfield W, Gokhale H, Gazzalle A, Waddell T, Liu M, Keshavjee S, Cypel M. Ali A, et al. Among authors: gokhale h. J Heart Lung Transplant. 2020 Jun;39(6):595-603. doi: 10.1016/j.healun.2020.03.027. Epub 2020 Apr 10. J Heart Lung Transplant. 2020. PMID: 32334946
Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs.
Wang A, Ribeiro RVP, Ali A, Brambate E, Abdelnour-Berchtold E, Michaelsen V, Zhang Y, Rahfeld P, Moon H, Gokhale H, Gazzalle A, Pal P, Liu M, Waddell TK, Cserti-Gazdewich C, Tinckam K, Kizhakkedathu JN, West L, Keshavjee S, Withers SG, Cypel M. Wang A, et al. Among authors: gokhale h. Sci Transl Med. 2022 Feb 16;14(632):eabm7190. doi: 10.1126/scitranslmed.abm7190. Epub 2022 Feb 16. Sci Transl Med. 2022. PMID: 35171649
L-alanyl-L-glutamine modified perfusate improves human lung cell functions and extend porcine ex vivo lung perfusion.
Huang L, Hough O, Vellanki RN, Takahashi M, Zhu Z, Xiang YY, Chen M, Gokhale H, Shan H, Soltanieh S, Jing L, Gao X, Wouters BG, Cypel M, Keshavjee S, Liu M. Huang L, et al. Among authors: gokhale h. J Heart Lung Transplant. 2023 Feb;42(2):183-195. doi: 10.1016/j.healun.2022.10.022. Epub 2022 Nov 3. J Heart Lung Transplant. 2023. PMID: 36411189
Strategies to prolong homeostasis of ex vivo perfused lungs.
Takahashi M, Andrew Cheung HY, Watanabe T, Zamel R, Cypel M, Liu M, Keshavjee S; Extended Pig EVLP Research Group. Takahashi M, et al. J Thorac Cardiovasc Surg. 2021 Jun;161(6):1963-1973. doi: 10.1016/j.jtcvs.2020.07.104. Epub 2020 Aug 13. J Thorac Cardiovasc Surg. 2021. PMID: 32958268 Free article.
Spiral CT angiography of the aorta.
Kopecky KK, Gokhale HS, Hawes DR. Kopecky KK, et al. Among authors: gokhale hs. Semin Ultrasound CT MR. 1996 Aug;17(4):304-15. doi: 10.1016/s0887-2171(96)90018-9. Semin Ultrasound CT MR. 1996. PMID: 8858770 Review.