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Adriforant is a functional antagonist of histamine receptor 4 and attenuates itch and skin inflammation in mice.
Uluckan Ö, Bruno S, Wang Y, Wack N, Wilzopolski J, Goetschy JF, Delucis-Bronn C, Urban B, Fehlmann D, Stark H, Hauchard A, Roussel E, Kempf D, Kaupmann K, Raulf F, Bäumer W, Röhn TA, Zerwes HG. Uluckan Ö, et al. Among authors: hauchard a. Eur J Pharmacol. 2023 Apr 15;945:175533. doi: 10.1016/j.ejphar.2023.175533. Epub 2023 Jan 21. Eur J Pharmacol. 2023. PMID: 36690055