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427 results

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Page 1
Multiomic foundations of human prefrontal cortex tissue function.
Kopell BH, Kaji DA, Liharska LE, Vornholt E, Valentine A, Lund A, Hashemi A, Thompson RC, Lohrenz T, Johnson JS, Bussola N, Cheng E, Park YJ, Shah P, Ma W, Searfoss R, Qasim S, Miller GM, Chand NM, Aristel A, Humphrey J, Wilkins L, Ziafat K, Silk H, Linares LM, Sullivan B, Feng C, Batten SR, Bang D, Barbosa LS, Twomey T, White JP, Vannucci M, Hadj-Amar B, Cohen V, Kota P, Moya E, Rieder MK, Figee M, Nadkarni GN, Breen MS, Kishida KT, Scarpa J, Ruderfer DM, Narain NR, Wang P, Kiebish MA, Schadt EE, Saez I, Montague PR, Beckmann ND, Charney AW. Kopell BH, et al. Among authors: schadt ee. medRxiv [Preprint]. 2024 May 17:2024.05.17.24307537. doi: 10.1101/2024.05.17.24307537. medRxiv. 2024. PMID: 38798344 Free PMC article. Preprint.
A study of gene expression in the living human brain.
Liharska LE, Park YJ, Ziafat K, Wilkins L, Silk H, Linares LM, Vornholt E, Sullivan B, Cohen V, Kota P, Feng C, Cheng E, Moya E, Thompson RC, Johnson JS, Rieder MK, Huang J, Scarpa J, Hashemi A, Polanco J, Levin MA, Nadkarni GN, Sebra R, Crary J, Schadt EE, Beckmann ND, Kopell BH, Charney AW. Liharska LE, et al. Among authors: schadt ee. medRxiv [Preprint]. 2023 Aug 1:2023.04.21.23288916. doi: 10.1101/2023.04.21.23288916. medRxiv. 2023. PMID: 37163086 Free PMC article. Preprint.
Characterizing cell type specific transcriptional differences between the living and postmortem human brain.
Vornholt E, Liharska LE, Cheng E, Hashemi A, Park YJ, Ziafat K, Wilkins L, Silk H, Linares LM, Thompson RC, Sullivan B, Moya E, Nadkarni GN, Sebra R, Schadt EE, Kopell BH, Charney AW, Beckmann ND. Vornholt E, et al. Among authors: schadt ee. medRxiv [Preprint]. 2024 May 1:2024.05.01.24306590. doi: 10.1101/2024.05.01.24306590. medRxiv. 2024. PMID: 38746297 Free PMC article. Preprint.
Divergent landscapes of A-to-I editing in postmortem and living human brain.
de Los Santos MR, Kopell BH, Grice AB, Ganesh G, Yang A, Amini P, Liharska LE, Vornholt E, Fullard JF, Dong P, Park E, Zipkowitz S, Kaji DA, Thompson RC, Liu D, Park YJ, Cheng E, Ziafat K, Moya E, Fennessy B, Wilkins L, Silk H, Linares LM, Sullivan B, Cohen V, Kota P, Feng C, Johnson JS, Rieder MK, Scarpa J, Nadkarni GN, Wang M, Zhang B, Sklar P, Beckmann ND, Schadt EE, Roussos P, Charney AW, Breen MS. de Los Santos MR, et al. Among authors: schadt ee. medRxiv [Preprint]. 2024 May 9:2024.05.06.24306763. doi: 10.1101/2024.05.06.24306763. medRxiv. 2024. Update in: Nat Commun. 2024 Jun 26;15(1):5366. doi: 10.1038/s41467-024-49268-z PMID: 38765961 Free PMC article. Updated. Preprint.
Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae.
Thompson RC, Simons NW, Wilkins L, Cheng E, Del Valle DM, Hoffman GE, Fennessy B, Mouskas K, Francoeur NJ, Johnson JS, Lepow L, Le Berichel J, Chang C, Beckmann AG, Wang YC, Nie K, Zaki N, Tuballes K, Barcessat V, Cedillo MA, Huckins L, Roussos P, Marron TU; Mount Sinai COVID-19 Biobank Team; Glicksberg BS, Nadkarni G, Gonzalez-Kozlova E, Kim-Schulze S, Sebra R, Merad M, Gnjatic S, Schadt EE, Charney AW, Beckmann ND. Thompson RC, et al. Among authors: schadt ee. medRxiv [Preprint]. 2021 Oct 5:2021.10.04.21264434. doi: 10.1101/2021.10.04.21264434. medRxiv. 2021. PMID: 34642700 Free PMC article. Preprint.
Peripheral Transcriptomics in Acute and Long-Term Kidney Dysfunction in SARS-CoV2 Infection.
Jayaraman P, Rajagopal M, Paranjpe I, Liharska L, Suarez-Farinas M, Thompson R, Del Valle DM, Beckmann N, Oh W, Gulamali FF, Kauffman J, Gonzalez-Kozlova E, Dellepiane S, Vasquez-Rios G, Vaid A, Jiang J, Chen A, Sakhuja A, Chen S, Kenigsberg E, He JC, Coca SG, Chan L, Schadt E, Merad M, Kim-Schulze S, Gnjatic S, Tsalik E, Langley R, Charney AW, Nadkarni GN. Jayaraman P, et al. medRxiv [Preprint]. 2023 Oct 27:2023.10.25.23297469. doi: 10.1101/2023.10.25.23297469. medRxiv. 2023. PMID: 37961671 Free PMC article. Preprint.
Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice.
Pan AL, Audrain M, Sakakibara E, Joshi R, Zhu X, Wang Q, Wang M, Beckmann ND, Schadt EE, Gandy S, Zhang B, Ehrlich ME, Salton SR. Pan AL, et al. Among authors: schadt ee. bioRxiv [Preprint]. 2023 Aug 25:2023.08.24.554335. doi: 10.1101/2023.08.24.554335. bioRxiv. 2023. Update in: Front Aging Neurosci. 2024 Jun 28;16:1400447. doi: 10.3389/fnagi.2024.1400447 PMID: 37662269 Free PMC article. Updated. Preprint.
Prediction of checkpoint inhibitor immunotherapy efficacy for cancer using routine blood tests and clinical data.
Yoo SK, Fitzgerald CW, Cho BA, Fitzgerald BG, Han C, Koh ES, Pandey A, Sfreddo H, Crowley F, Korostin MR, Debnath N, Leyfman Y, Valero C, Lee M, Vos JL, Lee AS, Zhao K, Lam S, Olumuyide E, Kuo F, Wilson EA, Hamon P, Hennequin C, Saffern M, Vuong L, Hakimi AA, Brown B, Merad M, Gnjatic S, Bhardwaj N, Galsky MD, Schadt EE, Samstein RM, Marron TU, Gönen M, Morris LGT, Chowell D. Yoo SK, et al. Among authors: schadt ee. Nat Med. 2025 Jan 6. doi: 10.1038/s41591-024-03398-5. Online ahead of print. Nat Med. 2025. PMID: 39762425
Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice.
Pan AL, Audrain M, Sakakibara E, Joshi R, Zhu X, Wang Q, Wang M, Beckmann ND, Schadt EE, Gandy S, Zhang B, Ehrlich ME, Salton SR. Pan AL, et al. Among authors: schadt ee. Front Aging Neurosci. 2024 Jun 28;16:1400447. doi: 10.3389/fnagi.2024.1400447. eCollection 2024. Front Aging Neurosci. 2024. PMID: 39006222 Free PMC article.
427 results