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Page 1
NK2R control of energy expenditure and feeding to treat metabolic diseases.
Sass F, Ma T, Ekberg JH, Kirigiti M, Ureña MG, Dollet L, Brown JM, Basse AL, Yacawych WT, Burm HB, Andersen MK, Nielsen TS, Tomlinson AJ, Dmytiyeva O, Christensen DP, Bader L, Vo CT, Wang Y, Rausch DM, Kristensen CK, Gestal-Mato M, In Het Panhuis W, Sjøberg KA, Kernodle S, Petersen JE, Pavlovskyi A, Sandhu M, Moltke I, Jørgensen ME, Albrechtsen A, Grarup N, Babu MM, Rensen PCN, Kooijman S, Seeley RJ, Worthmann A, Heeren J, Pers TH, Hansen T, Gustafsson MBF, Tang-Christensen M, Kilpeläinen TO, Myers MG Jr, Kievit P, Schwartz TW, Hansen JB, Gerhart-Hines Z. Sass F, et al. Among authors: babu mm. Nature. 2024 Nov;635(8040):987-1000. doi: 10.1038/s41586-024-08207-0. Epub 2024 Nov 13. Nature. 2024. PMID: 39537932 Free PMC article.
Somatic mitochondrial DNA mutations are a source of heterogeneity among primary leukemic cells.
McCastlain K, Welsh C, Ni Y, Ding L, Franco M, Autry R, Sejdiu B, Chang TC, Chen W, Wu H, Pan Q, Gonzalez-Pena V, Schreiner P, Arunachalam S, Joo J, Li B, Shen S, Brady S, Zhang J, Gawad C, Evans W, Babu MM, Khrapko K, Wu G, Yu J, Pounds S, Kundu M. McCastlain K, et al. Among authors: babu mm. medRxiv [Preprint]. 2024 Sep 27:2024.09.26.24314381. doi: 10.1101/2024.09.26.24314381. medRxiv. 2024. PMID: 39398996 Free PMC article. Preprint.
An early, novel arginine methylation of KCa3.1 attenuates subsequent T cell exhaustion.
Sharma P, Guo A, Poudel S, Boada-Romero E, Verbist KC, Palacios G, Immadisetty K, Chen MJ, Haydar D, Mishra A, Peng J, Babu MM, Krenciute G, Glazer ES, Green DR. Sharma P, et al. Among authors: babu mm. bioRxiv [Preprint]. 2024 Nov 20:2024.05.09.593421. doi: 10.1101/2024.05.09.593421. bioRxiv. 2024. PMID: 38798680 Free PMC article. Preprint.
Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity.
Zoine JT, Immadisetty K, Ibanez-Vega J, Moore SE, Nevitt C, Thanekar U, Tian L, Karouni A, Chockley PJ, Arthur B, Sheppard H, Klco JM, Langfitt DM, Krenciute G, Gottschalk S, Babu MM, Velasquez MP. Zoine JT, et al. Among authors: babu mm. Cell Rep Med. 2024 Feb 20;5(2):101422. doi: 10.1016/j.xcrm.2024.101422. Epub 2024 Feb 12. Cell Rep Med. 2024. PMID: 38350450 Free PMC article.
Dynamic conformational changes of a tardigrade group-3 late embryogenesis abundant protein modulate membrane biophysical properties.
Li XH, Yu CWH, Gomez-Navarro N, Stancheva V, Zhu H, Murthy A, Wozny M, Malhotra K, Johnson CM, Blackledge M, Santhanam B, Liu W, Huang J, Freund SMV, Miller EA, Babu MM. Li XH, et al. Among authors: babu mm. PNAS Nexus. 2024 Jan 18;3(1):pgae006. doi: 10.1093/pnasnexus/pgae006. eCollection 2024 Jan. PNAS Nexus. 2024. PMID: 38269070 Free PMC article.
Molecular determinants of ligand efficacy and potency in GPCR signaling.
Heydenreich FM, Marti-Solano M, Sandhu M, Kobilka BK, Bouvier M, Babu MM. Heydenreich FM, et al. Among authors: babu mm. Science. 2023 Dec 22;382(6677):eadh1859. doi: 10.1126/science.adh1859. Epub 2023 Dec 22. Science. 2023. PMID: 38127743 Free PMC article.
Modular chimeric cytokine receptors with leucine zippers enhance the antitumour activity of CAR T cells via JAK/STAT signalling.
Bell M, Lange S, Sejdiu BI, Ibanez J, Shi H, Sun X, Meng X, Nguyen P, Sutton M, Wagner J, Kc A, Langfitt D, Patil SL, Tan H, Pandey RV, Li Y, Yuan ZF, Anido AA, Ho M, Sheppard H, Vogel P, Yu J, Peng J, Chi H, Babu MM, Krenciute G, Gottschalk S. Bell M, et al. Among authors: babu mm. Nat Biomed Eng. 2024 Apr;8(4):380-396. doi: 10.1038/s41551-023-01143-w. Epub 2023 Nov 30. Nat Biomed Eng. 2024. PMID: 38036617 Free PMC article.
188 results