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244 results

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Page 1
Analysis of cell free DNA to predict outcome to bevacizumab therapy in colorectal cancer patients.
Venken T, Miller IS, Arijs I, Thomas V, Barat A, Betge J, Zhan T, Gaiser T, Ebert MP, O'Farrell AC, Prehn J, Klinger R, O'Connor DP, Moulton B, Murphy V, Serna G, Nuciforo PG, McDermott R, Bird B, Leonard G, Grogan L, Horgan A, Schulte N, Moehler M, Lambrechts D, Byrne AT. Venken T, et al. Among authors: o connor dp. NPJ Genom Med. 2024 May 29;9(1):33. doi: 10.1038/s41525-024-00415-x. NPJ Genom Med. 2024. PMID: 38811554 Free PMC article.
Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer.
Zuurbier L, Rahman A, Cordes M, Scheick J, Wong TJ, Rustenburg F, Joseph JC, Dynoodt P, Casey R, Drillenburg P, Gerhards M, Barat A, Klinger R, Fender B, O'Connor DP, Betge J, Ebert MP, Gaiser T, Prehn JHM, Griffioen AW, van Grieken NCT, Ylstra B, Byrne AT, van der Flier LG, Gallagher WM, Postel R. Zuurbier L, et al. Oncotarget. 2017 Jun 27;8(26):42949-42961. doi: 10.18632/oncotarget.17306. Oncotarget. 2017. PMID: 28487489 Free PMC article.
Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab.
van Dijk E, Biesma HD, Cordes M, Smeets D, Neerincx M, Das S, Eijk PP, Murphy V, Barat A, Bacon O, Prehn JHM, Betge J, Gaiser T, Fender B, Meijer GA, McNamara DA, Klinger R, Koopman M, Ebert MPA, Kay EW, Hennessey BT, Verheul HMW, Gallagher WM, O'Connor DP, Punt CJA, Loupakis F, Lambrechts D, Byrne AT, van Grieken NCT, Ylstra B. van Dijk E, et al. J Clin Oncol. 2018 Jul 10;36(20):2052-2060. doi: 10.1200/JCO.2017.77.1782. Epub 2018 May 24. J Clin Oncol. 2018. PMID: 29792754 Clinical Trial.
Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy.
Smeets D, Miller IS, O'Connor DP, Das S, Moran B, Boeckx B, Gaiser T, Betge J, Barat A, Klinger R, van Grieken NCT, Cremolini C, Prenen H, Mazzone M, Depreeuw J, Bacon O, Fender B, Brady J, Hennessy BT, McNamara DA, Kay E, Verheul HM, Maarten N, Gallagher WM, Murphy V, Prehn JHM, Koopman M, Punt CJA, Loupakis F, Ebert MPA, Ylstra B, Lambrechts D, Byrne AT. Smeets D, et al. Nat Commun. 2018 Oct 5;9(1):4112. doi: 10.1038/s41467-018-06567-6. Nat Commun. 2018. PMID: 30291241 Free PMC article.
Combination of variations in inflammation- and endoplasmic reticulum-associated genes as putative biomarker for bevacizumab response in KRAS wild-type colorectal cancer.
Barat A, Smeets D, Moran B, Zhang W, Cao S, Das S, Klinger R, Betge J, Murphy V, Bacon O, Kay EW, Van Grieken NCT, Verheul HMW, Gaiser T, Schulte N, Ebert MP, Fender B, Hennessy BT, McNamara DA, O'Connor D, Gallagher WM, Cremolini C, Loupakis F, Parikh A, Mancao C, Ylstra B, Lambrechts D, Lenz HJ, Byrne AT, Prehn JHM. Barat A, et al. Sci Rep. 2020 Jun 17;10(1):9778. doi: 10.1038/s41598-020-65869-2. Sci Rep. 2020. PMID: 32555399 Free PMC article.
Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach.
Moran B, Das S, Smeets D, Peutman G, Klinger R, Fender B, Connor K, Ebert M, Gaiser T, Prehn JH, Bacon O, Kay E, Hennessy B, Murphy V, Ylstra B, Lambrechts D, Byrne AT, Gallagher WM, O'Connor DP. Moran B, et al. Oncotarget. 2017 Jul 18;8(29):48126-48137. doi: 10.18632/oncotarget.18296. Oncotarget. 2017. PMID: 28611295 Free PMC article.
Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects.
Miller IS, Khan S, Shiels LP, Das S, O' Farrell AC, Connor K, Lafferty A, Moran B, Isella C, Loadman P, Conroy E, Cohrs S, Schibli R, Kerbel RS, Gallagher WM, Marangoni E, Bennett K, O' Connor DP, Dwyer RM, Byrne AT. Miller IS, et al. Cancer Med. 2022 Oct;11(20):3820-3836. doi: 10.1002/cam4.4756. Epub 2022 Apr 17. Cancer Med. 2022. PMID: 35434898 Free PMC article.
microRNAs: a new class of breast cancer biomarkers.
Mulrane L, Klinger R, McGee SF, Gallagher WM, O'Connor DP. Mulrane L, et al. Expert Rev Mol Diagn. 2014 Apr;14(3):347-63. doi: 10.1586/14737159.2014.901153. Expert Rev Mol Diagn. 2014. PMID: 24649821 Review.
Vitamin D receptor as a target for breast cancer therapy.
Murray A, Madden SF, Synnott NC, Klinger R, O'Connor D, O'Donovan N, Gallagher W, Crown J, Duffy MJ. Murray A, et al. Endocr Relat Cancer. 2017 Apr;24(4):181-195. doi: 10.1530/ERC-16-0463. Epub 2017 Feb 17. Endocr Relat Cancer. 2017. PMID: 28213567
Master Transcription Regulators and Transcription Factors Regulate Immune-Associated Differences Between Patients of African and European Ancestry With Colorectal Cancer.
Myer PA, Kim H, Blümel AM, Finnegan E, Kel A, Thompson TV, Greally JM, Prehn JH, O'Connor DP, Friedman RA, Floratos A, Das S. Myer PA, et al. Among authors: o connor dp. Gastro Hep Adv. 2022;1(3):328-341. doi: 10.1016/j.gastha.2022.01.004. Gastro Hep Adv. 2022. PMID: 35711675 Free PMC article.
244 results