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118 results

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Page 1
Inhibition of hepatic p63 ameliorates steatohepatitis with fibrosis in mice.
Fondevila MF, Novoa E, Fernandez U, Dorta V, Parracho T, Kreimeyer H, Garcia-Vence M, Chantada-Vazquez MP, Bravo SB, Porteiro B, Cabaleiro A, Koning M, Senra A, Souto Y, Verheij J, Guallar D, Fidalgo M, Meijnikman AS, da Silva Lima N, Dieguez C, Gonzalez-Rellan MJ, Nogueiras R. Fondevila MF, et al. Among authors: novoa e. Mol Metab. 2024 Jul;85:101962. doi: 10.1016/j.molmet.2024.101962. Epub 2024 May 28. Mol Metab. 2024. PMID: 38815625 Free PMC article.
Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.
Gonzalez-Rellan MJ, Parracho T, Heras V, Rodriguez A, Fondevila MF, Novoa E, Lima N, Varela-Rey M, Senra A, Chantada-Vazquez MDP, Ameneiro C, Bernardo G, Fernandez-Ramos D, Lopitz-Otsoa F, Bilbao J, Guallar D, Fidalgo M, Bravo S, Dieguez C, Martinez-Chantar ML, Millet O, Mato JM, Schwaninger M, Prevot V, Crespo J, Frühbeck G, Iruzubieta P, Nogueiras R. Gonzalez-Rellan MJ, et al. Among authors: novoa e. Mol Metab. 2023 Sep;75:101776. doi: 10.1016/j.molmet.2023.101776. Epub 2023 Jul 13. Mol Metab. 2023. PMID: 37453647 Free PMC article.
Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism.
Gonzalez-Rellan MJ, Fernández U, Parracho T, Novoa E, Fondevila MF, da Silva Lima N, Ramos L, Rodríguez A, Serrano-Maciá M, Perez-Mejias G, Chantada-Vazquez P, Riobello C, Veyrat-Durebex C, Tovar S, Coppari R, Woodhoo A, Schwaninger M, Prevot V, Delgado TC, Lopez M, Diaz-Quintana A, Dieguez C, Guallar D, Frühbeck G, Diaz-Moreno I, Bravo SB, Martinez-Chantar ML, Nogueiras R. Gonzalez-Rellan MJ, et al. Among authors: novoa e. Cell Metab. 2023 Sep 5;35(9):1630-1645.e5. doi: 10.1016/j.cmet.2023.07.003. Epub 2023 Aug 3. Cell Metab. 2023. PMID: 37541251 Free PMC article.
Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance.
Dragano NRV, Milbank E, Haddad-Tóvolli R, Garrido-Gil P, Nóvoa E, Fondevilla MF, Capelli V, Zanesco AM, Solon C, Morari J, Pires L, Estevez-Salguero Á, Beiroa D, González-García I, Barca-Mayo O, Diéguez C, Nogueiras R, Labandeira-García JL, Rexen Ulven E, Ulven T, Claret M, Velloso LA, López M. Dragano NRV, et al. Among authors: novoa e. Mol Metab. 2024 Jan;79:101840. doi: 10.1016/j.molmet.2023.101840. Epub 2023 Nov 29. Mol Metab. 2024. PMID: 38036170 Free PMC article.
p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway.
Fondevila MF, Novoa E, Gonzalez-Rellan MJ, Fernandez U, Heras V, Porteiro B, Parracho T, Dorta V, Riobello C, da Silva Lima N, Seoane S, Garcia-Vence M, Chantada-Vazquez MP, Bravo SB, Senra A, Leiva M, Marcos M, Sabio G, Perez-Fernandez R, Dieguez C, Prevot V, Schwaninger M, Woodhoo A, Martinez-Chantar ML, Schwabe R, Cubero FJ, Varela-Rey M, Crespo J, Iruzubieta P, Nogueiras R. Fondevila MF, et al. Among authors: novoa e. Cell Rep Med. 2024 Feb 20;5(2):101401. doi: 10.1016/j.xcrm.2024.101401. Epub 2024 Feb 9. Cell Rep Med. 2024. PMID: 38340725 Free PMC article.
Mitochondrial antiviral signaling protein enhances MASLD progression through the ERK/TNFα/NFκβ pathway.
Nóvoa E, da Silva Lima N, Gonzalez-Rellan MJ, Chantada-Vazquez MDP, Verheij J, Rodriguez A, Esquinas-Roman EM, Fondevila MF, Koning M, Fernandez U, Cabaleiro A, Parracho T, Iglesias-Moure J, Seoane S, Porteiro B, Escudero A, Senra A, Perez-Fernandez R, López M, Fidalgo M, Guallar D, Martinez-Chantar ML, Dieguez C, Varela-Rey M, Prevot V, Schwaninger M, Meijnikman A, Bravo SB, Frühbeck G, Nogueiras R. Nóvoa E, et al. Hepatology. 2024 May 19. doi: 10.1097/HEP.0000000000000930. Online ahead of print. Hepatology. 2024. PMID: 38761407
GLP-1 and GIP agonism has no direct actions in human hepatocytes or hepatic stellate cells.
da Silva Lima N, Cabaleiro A, Novoa E, Riobello C, Knerr PJ, He Y, Esquinas-Román EM, González-García I, Prevot V, Schwaninger M, Dieguez C, López M, Müller TD, Varela-Rey M, Douros JD, Nogueiras R. da Silva Lima N, et al. Among authors: novoa e. Cell Mol Life Sci. 2024 Nov 28;81(1):468. doi: 10.1007/s00018-024-05507-6. Cell Mol Life Sci. 2024. PMID: 39607493 Free PMC article.
Epitranscriptomic rRNA fingerprinting reveals tissue-of-origin and tumor-specific signatures.
Milenkovic I, Cruciani S, Llovera L, Lucas MC, Medina R, Pauli C, Heid D, Muley T, Schneider MA, Klotz LV, Allgäuer M, Lattuca R, Lafontaine DLJ, Müller-Tidow C, Novoa EM. Milenkovic I, et al. Among authors: novoa em. Mol Cell. 2025 Jan 2;85(1):177-190.e7. doi: 10.1016/j.molcel.2024.11.014. Epub 2024 Dec 10. Mol Cell. 2025. PMID: 39662470
118 results