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Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification.
de Vries PS, Conomos MP, Singh K, Nicholson CJ, Jain D, Hasbani NR, Jiang W, Lee S, Lino Cardenas CL, Lutz SM, Wong D, Guo X, Yao J, Young EP, Tcheandjieu C, Hilliard AT, Bis JC, Bielak LF, Brown MR, Musharoff S, Clarke SL, Terry JG, Palmer ND, Yanek LR, Xu H, Heard-Costa N, Wessel J, Selvaraj MS, Li RH, Sun X, Turner AW, Stilp AM, Khan A, Newman AB, Rasheed A, Freedman BI, Kral BG, McHugh CP, Hodonsky C, Saleheen D, Herrington DM, Jacobs DR Jr, Nickerson DA, Boerwinkle E, Wang FF, Heiss G, Jun G, Kinney GL, Sigurslid HH, Doddapaneni H, Hall IM, Bensenor IM, Broome J, Crapo JD, Wilson JG, Smith JA, Blangero J, Vargas JD, Mosquera JV, Smith JD, Viaud-Martinez KA, Ryan KA, Young KA, Taylor KD, Lange LA, Emery LS, Bittencourt MS, Budoff MJ, Montasser ME, Yu M, Mahaney MC, Mahamdeh MS, Fornage M, Franceschini N, Lotufo PA, Natarajan P, Wong Q, Mathias RA, Gibbs RA, Do R, Mehran R, Tracy RP, Kim RW, Nelson SC, Damrauer SM, Kardia SLR, Rich SS, Fuster V, Napolioni V, Zhao W, Tian W, Yin X, Min YI, Manning AK, Peloso G, Kelly TN, O'Donnell CJ, Morrison AC, Curran JE, Zapol WM, Bowden DW, Becker LC, Correa A, Mitchell BD, Psaty BM, Carr JJ, Pereira AC, Assimes TL, Stitziel NO, Hokanson JE… See abstract for full author list ➔ de Vries PS, et al. Among authors: miller cl. Nat Cardiovasc Res. 2023 Dec;2(12):1159-1172. doi: 10.1038/s44161-023-00375-y. Epub 2023 Dec 4. Nat Cardiovasc Res. 2023. PMID: 38817323 Free PMC article.
A Large-Scale Genome-Wide Gene-Sleep Interaction Study in 732,564 Participants Identifies Lipid Loci Explaining Sleep-Associated Lipid Disturbances.
Noordam R, Wang W, Nagarajan P, Wang H, Brown MR, Bentley AR, Hui Q, Kraja AT, Morrison JL, O'Connel JR, Lee S, Schwander K, Bartz TM, de las Fuentes L, Feitosa MF, Guo X, Hanfei X, Harris SE, Huang Z, Kals M, Lefevre C, Mangino M, Milaneschi Y, van der Most P, Pacheco NL, Palmer ND, Rao V, Rauramaa R, Sun Q, Tabara Y, Vojinovic D, Wang Y, Weiss S, Yang Q, Zhao W, Zhu W, Abu Yusuf Ansari M, Aschard H, Anugu P, Assimes TL, Attia J, Baker LD, Ballantyne C, Bazzano L, Boerwinkle E, Cade B, Chen HH, Chen W, Ida Chen YD, Chen Z, Cho K, De Anda-Duran I, Dimitrov L, Do A, Edwards T, Faquih T, Hingorani A, Fisher-Hoch SP, Gaziano JM, Gharib SA, Giri A, Ghanbari M, Grabe HJ, Graff M, Gu CC, He J, Heikkinen S, Hixson J, Ho YL, Hood MM, Houghton SC, Karvonen-Gutierrez CA, Kawaguchi T, Kilpeläinen TO, Komulainen P, Lin HJ, Linchangco GV, Luik AI, Ma J, Meigs JB, McCormick JB, Menni C, Nolte IM, Norris JM, Petty LE, Polikowsky HG, Raffield LM, Rich SS, Riha RL, Russ TC, Ruiz-Narvaez EA, Sitlani CM, Smith JA, Snieder H, Sofer T, Shen B, Tang J, Taylor KD, Teder-Laving M, Triatin R, Tsai MY, Völzke H, Westerman KE, Xia R, Yao J, Young KL, Zhang R, Zonderman AB, Zhu X, Below JE, Cox SR, Evans M, … See abstract for full author list ➔ Noordam R, et al. Among authors: miller cl. medRxiv [Preprint]. 2024 Sep 4:2024.09.02.24312466. doi: 10.1101/2024.09.02.24312466. medRxiv. 2024. PMID: 39281768 Free PMC article. Preprint.
Single cell variant to enhancer to gene map for coronary artery disease.
Amrute JM, Lee PC, Eres I, Lee CJM, Bredemeyer A, Sheth MU, Yamawaki T, Gurung R, Anene-Nzelu C, Qiu WL, Kundu S, Li DY, Ramste M, Lu D, Tan A, Kang CJ, Wagoner RE, Alisio A, Cheng P, Zhao Q, Miller CL, Hall IM, Gupta RM, Hsu YH, Haldar SM, Lavine KJ, Jackson S, Andersson R, Engreitz JM, Foo RS, Li CM, Ason B, Quertermous T, Stitziel NO. Amrute JM, et al. Among authors: miller cl. medRxiv [Preprint]. 2024 Nov 13:2024.11.13.24317257. doi: 10.1101/2024.11.13.24317257. medRxiv. 2024. PMID: 39606421 Free PMC article. Preprint.
INKILN is a novel long noncoding RNA promoting vascular smooth muscle inflammation via scaffolding MKL1 and USP10.
Zhang W, Zhao J, Deng L, Ishimwe N, Pauli J, Wu W, Shan S, Kempf W, Ballantyne MD, Kim D, Lyu Q, Bennett M, Rodor J, Turner AW, Lu YW, Gao P, Choi M, Warthi G, Kim HW, Barroso MM, Bryant WB, Miller CL, Weintraub NL, Maegdefessel L, Miano JM, Baker AH, Long X. Zhang W, et al. Among authors: miller cl. bioRxiv [Preprint]. 2023 Jan 9:2023.01.07.522948. doi: 10.1101/2023.01.07.522948. bioRxiv. 2023. Update in: Circulation. 2023 Jul 4;148(1):47-67. doi: 10.1161/CIRCULATIONAHA.123.063760 PMID: 36711681 Free PMC article. Updated. Preprint.
Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosis.
Su M, Zhao W, Jiang H, Zhao Y, Liao Z, Liu Z, Xu M, Jiang S, Wu L, Yang Y, Wang Z, Zeng Z, Fang Y, Tang C, Miller CL, Evans PC, Wang L, Banach M, Jo H, Berk BC, Offermanns S, Huang Y, Ge J, Xu S, Weng J. Su M, et al. Among authors: miller cl. Nat Cardiovasc Res. 2025 Jan 10. doi: 10.1038/s44161-024-00591-0. Online ahead of print. Nat Cardiovasc Res. 2025. PMID: 39794479
Vascular smooth muscle cell plasticity in the tumor microenvironment.
Bell CF, Baylis RA, Lopez NG, Ma WF, Gao H, Wang F, Bamezai S, Fu C, Kojima Y, Adkar SS, Luo L, Miller CL, Leeper NJ. Bell CF, et al. Among authors: miller cl. Cancer Commun (Lond). 2024 Dec 8. doi: 10.1002/cac2.12635. Online ahead of print. Cancer Commun (Lond). 2024. PMID: 39648671 No abstract available.
Atheroma transcriptomics identifies ARNTL as a smooth muscle cell regulator and with clinical and genetic data improves risk stratification.
Narayanan S, Vuckovic S, Bergman O, Wirka R, Verdezoto Mosquera J, Chen QS, Baldassarre D, Tremoli E, Veglia F, Lengquist M, Aherahrrou R, Razuvaev A, Gigante B, Björck HM, Miller CL, Quertermous T, Hedin U, Matic L. Narayanan S, et al. Among authors: miller cl. Eur Heart J. 2024 Nov 18:ehae768. doi: 10.1093/eurheartj/ehae768. Online ahead of print. Eur Heart J. 2024. PMID: 39552248
The impact of post-remission granulocyte colony-stimulating factor use in the phase 3 studies of venetoclax combination treatments in patients with newly diagnosed acute myeloid leukemia.
DiNardo CD, Pratz KW, Panayiotidis P, Wei X, Vorobyev V, Illés Á, Kim I, Ivanov V, Ku G, Miller CL, Zhang M, Tatsch F, Potluri J, Schmidt X, Récher C. DiNardo CD, et al. Among authors: miller cl. Am J Hematol. 2025 Jan;100(1):185-188. doi: 10.1002/ajh.27515. Epub 2024 Nov 1. Am J Hematol. 2025. PMID: 39487568 Free PMC article. No abstract available.
554 results