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Kinetics of nirogacestat-mediated increases in B-cell maturation antigen on plasma cells inform therapeutic combinations in multiple myeloma.
Shearer T, Comstock M, Williams RL, Johnson MC, Cendrowicz E, Leonowens C, Smith M, Baughman TM, Breitbach CJ, Cheng S, Green DJ. Shearer T, et al. Among authors: johnson mc. Cancer Res Commun. 2024 Nov 11. doi: 10.1158/2767-9764.CRC-24-0075. Online ahead of print. Cancer Res Commun. 2024. PMID: 39530736 Free article.
Autoinhibition of dimeric NINJ1 prevents plasma membrane rupture.
Pourmal S, Truong ME, Johnson MC, Yang Y, Zhou L, Alegre K, Stowe IB, Gupta S, Chen PA, Zhang Y, Rohou A, Newton K, Kayagaki N, Dixit VM, Deshpande I. Pourmal S, et al. Among authors: johnson mc. Nature. 2024 Oct 30. doi: 10.1038/s41586-024-08273-4. Online ahead of print. Nature. 2024. PMID: 39476863
511 results