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762 results

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Chronic Obstructive Pulmonary Disease Exacerbations Increase the Risk of Subsequent Cardiovascular Events: A Longitudinal Analysis of the COPDGene Study.
Yang HM, Ryu MH, Carey VJ, Kinney GL, Hokanson JE, Dransfield MT, Hersh CP, Silverman EK; COPDGene Investigators †. Yang HM, et al. Among authors: silverman ek. J Am Heart Assoc. 2024 Jun 4;13(11):e033882. doi: 10.1161/JAHA.123.033882. Epub 2024 May 31. J Am Heart Assoc. 2024. PMID: 38818936 Free PMC article.
Joint clinical and molecular subtyping of COPD with variational autoencoders.
Maiorino E, De Marzio M, Xu Z, Yun JH, Chase RP, Hersh CP, Weiss ST, Silverman EK, Castaldi PJ, Glass K. Maiorino E, et al. Among authors: silverman ek. medRxiv [Preprint]. 2024 Jan 10:2023.08.19.23294298. doi: 10.1101/2023.08.19.23294298. medRxiv. 2024. PMID: 38260473 Free PMC article. Preprint.
Fast computation of the eigensystem of genomic similarity matrices.
Hahn G, Lutz SM, Hecker J, Prokopenko D, Cho MH, Silverman EK, Weiss ST, Lange C. Hahn G, et al. Among authors: silverman ek. BMC Bioinformatics. 2024 Jan 25;25(1):43. doi: 10.1186/s12859-024-05650-8. BMC Bioinformatics. 2024. PMID: 38273228 Free PMC article.
Computational Deconvolution of Cell Type-Specific Gene Expression in COPD and IPF Lungs Reveals Disease Severity Associations.
Ryu MH, Yun JH, Kim K, Gentili M, Ghosh A, Sciurba F, Barwick L, Limper A, Criner G, Brown KK, Wise R, Martinez FJ, Flaherty KR, Cho MH, Castaldi PJ, DeMeo DL, Silverman EK, Hersh CP, Morrow JD. Ryu MH, et al. Among authors: silverman ek. medRxiv [Preprint]. 2024 Apr 24:2024.03.26.24304775. doi: 10.1101/2024.03.26.24304775. medRxiv. 2024. Update in: BMC Genomics. 2024 Dec 18;25(1):1192. doi: 10.1186/s12864-024-11031-5 PMID: 38585732 Free PMC article. Updated. Preprint.
Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes.
Moll M, Hecker J, Platig J, Zhang J, Ghosh AJ, Pratte KA, Wang RS, Hill D, Konigsberg IR, Chiles JW, Hersh CP, Castaldi PJ, Glass K, Dy JG, Sin DD, Tal-Singer R, Mouded M, Rennard SI, Anderson GP, Kinney GL, Bowler RP, Curtis JL, McDonald ML, Silverman EK, Hobbs BD, Cho MH. Moll M, et al. Among authors: silverman ek. medRxiv [Preprint]. 2024 May 20:2024.05.20.24307621. doi: 10.1101/2024.05.20.24307621. medRxiv. 2024. Update in: EBioMedicine. 2024 Dec;110:105429. doi: 10.1016/j.ebiom.2024.105429 PMID: 38826461 Free PMC article. Updated. Preprint.
A protein risk score for all-cause and respiratory-specific mortality in non-Hispanic white and African American individuals who smoke.
Moll M, Pratte KA, Debban CL, Liu C, Belinsky SA, Picchi M, Konigsberg I, Tern C, Rijhwani H, Hobbs BD, Silverman EK, Tesfaigzi Y, Rich SS, Manichaikul A, Rotter JI, Bowler RP, Cho MH. Moll M, et al. Among authors: silverman ek. Sci Rep. 2024 Sep 4;14(1):20618. doi: 10.1038/s41598-024-71714-7. Sci Rep. 2024. PMID: 39232179 Free PMC article.
Determinants of mosaic chromosomal alteration fitness.
Pershad Y, Mack T, Poisner H, Jakubek YA, Stilp AM, Mitchell BD, Lewis JP, Boerwinkle E, Loos RJF, Chami N, Wang Z, Barnes K, Pankratz N, Fornage M, Redline S, Psaty BM, Bis JC, Shojaie A, Silverman EK, Cho MH, Yun JH, DeMeo D, Levy D, Johnson AD, Mathias RA, Taub MA, Arnett D, North KE, Raffield LM, Carson AP, Doyle MF, Rich SS, Rotter JI, Guo X, Cox NJ, Roden DM, Franceschini N, Desai P, Reiner AP, Auer PL, Scheet PA, Jaiswal S, Weinstock JS, Bick AG. Pershad Y, et al. Among authors: silverman ek. Nat Commun. 2024 May 7;15(1):3800. doi: 10.1038/s41467-024-48190-8. Nat Commun. 2024. PMID: 38714703 Free PMC article.
Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium.
Jiang MZ, Gaynor SM, Li X, Van Buren E, Stilp A, Buth E, Wang FF, Manansala R, Gogarten SM, Li Z, Polfus LM, Salimi S, Bis JC, Pankratz N, Yanek LR, Durda P, Tracy RP, Rich SS, Rotter JI, Mitchell BD, Lewis JP, Psaty BM, Pratte KA, Silverman EK, Kaplan RC, Avery C, North KE, Mathias RA, Faraday N, Lin H, Wang B, Carson AP, Norwood AF, Gibbs RA, Kooperberg C, Lundin J, Peters U, Dupuis J, Hou L, Fornage M, Benjamin EJ, Reiner AP, Bowler RP, Lin X, Auer PL, Raffield LM; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Inflammation Working Group. Jiang MZ, et al. Among authors: silverman ek. Hum Mol Genet. 2024 Aug 6;33(16):1429-1441. doi: 10.1093/hmg/ddae050. Hum Mol Genet. 2024. PMID: 38747556
Implications of Race Adjustment in Lung-Function Equations.
Diao JA, He Y, Khazanchi R, Nguemeni Tiako MJ, Witonsky JI, Pierson E, Rajpurkar P, Elhawary JR, Melas-Kyriazi L, Yen A, Martin AR, Levy S, Patel CJ, Farhat M, Borrell LN, Cho MH, Silverman EK, Burchard EG, Manrai AK. Diao JA, et al. Among authors: silverman ek. N Engl J Med. 2024 Jun 13;390(22):2083-2097. doi: 10.1056/NEJMsa2311809. Epub 2024 May 19. N Engl J Med. 2024. PMID: 38767252 Free PMC article.
762 results