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Structural Convergence and Water-Mediated Substrate Mimicry Enable Broad Neuraminidase Inhibition by Human Antibodies.
Lederhofer J, Borst AJ, Nguyen L, Gillespie RA, Williams CJ, Walker EL, Raab JE, Yap C, Ellis D, Creanga A, Tan HX, Do THT, Ravichandran M, McDermott AB, Sage VL, Andrews SF, Graham BS, Wheatley AK, Reed DS, King NP, Kanekiyo M. Lederhofer J, et al. Among authors: reed ds. bioRxiv [Preprint]. 2024 Dec 3:2024.11.27.625426. doi: 10.1101/2024.11.27.625426. bioRxiv. 2024. PMID: 39677750 Free PMC article. Preprint.
Vaccination with different group 2 influenza subtypes alters epitope targeting and breadth of hemagglutinin stem-specific human B cells.
Mantus GE, Chopde AJ, Gorman J, Cominsky LY, Ourahmane A, Creanga A, Shimberg GD, Gillespie RA, Van Wazer DJ, Zhou T, Gajjala SR, Williams C, Maestle E, Reed DS, Serebryannyy L, Costner P, Holman L, Casazza JP, Koup RA, Dropulic LK, Kwong PD, McDermott AB, Kanekiyo M, Andrews SF. Mantus GE, et al. Among authors: reed ds. Sci Transl Med. 2025 Jan;17(779):eadr8373. doi: 10.1126/scitranslmed.adr8373. Epub 2025 Jan 1. Sci Transl Med. 2025. PMID: 39742506
Pre-existing H1N1 immunity reduces severe disease with bovine H5N1 influenza virus.
Le Sage V, Werner BD, Merrbach GA, Petnuch SE, O'Connell AK, Simmons HC, McCarthy KR, Reed DS, Moncla LH, Bhavsar D, Krammer F, Crossland NA, McElroy AK, Duprex WP, Lakdawala SS. Le Sage V, et al. Among authors: reed ds. bioRxiv [Preprint]. 2024 Oct 23:2024.10.23.619881. doi: 10.1101/2024.10.23.619881. bioRxiv. 2024. PMID: 39484442 Free PMC article. Preprint.
Cytomegalovirus vaccine vector-induced effector memory CD4 + T cells protect cynomolgus macaques from lethal aerosolized heterologous avian influenza challenge.
Malouli D, Tiwary M, Gilbride RM, Morrow DW, Hughes CM, Selseth A, Penney T, Castanha P, Wallace M, Yeung Y, Midgett M, Williams C, Reed J, Yu Y, Gao L, Yun G, Treaster L, Laughlin A, Lundy J, Tisoncik-Go J, Whitmore LS, Aye PP, Schiro F, Dufour JP, Papen CR, Taher H, Picker LJ, Früh K, Gale M Jr, Maness NJ, Hansen SG, Barratt-Boyes S, Reed DS, Sacha JB. Malouli D, et al. Among authors: reed ds. Nat Commun. 2024 Jul 19;15(1):6007. doi: 10.1038/s41467-024-50345-6. Nat Commun. 2024. PMID: 39030218 Free PMC article.
No evidence for enhanced disease with human polyclonal SARS-CoV-2 antibody in the ferret model.
Reed DS, McElroy AK, Barbeau DJ, McMillen CM, Tilston-Lunel NL, Nambulli S, Cottle E, Gilliland TC, Rannulu H, Lundy J, Olsen EL, O'Malley KJ, Xia M, Hartman AL, Luke TC, Egland K, Bausch C, Wu H, Sullivan EJ, Klimstra WB, Duprex WP. Reed DS, et al. PLoS One. 2024 Jun 20;19(6):e0290909. doi: 10.1371/journal.pone.0290909. eCollection 2024. PLoS One. 2024. PMID: 38900732 Free PMC article.
138 results