Xu J - Search Results

1

UBR1 Promotes Sex-Dependent ACE2 Ubiquitination in Hypertension.

Elgazzaz M, Lakkappa N, Berdasco C, Mohan UP, Nuzzo A, Restivo L, Martinez A, Scarborough A, Guidry JJ, Sriramula S, Xu J, Daoud H, Mendiola Plá MA, Bowles DE, Beyer AM, Mauvais-Jarvis F, Yue X, Filipeanu CM, Lazartigues E. Elgazzaz M, et al. Among authors: xu j. medRxiv [Preprint]. 2024 May 25:2024.05.23.24307722. doi: 10.1101/2024.05.23.24307722. medRxiv. 2024. Update in: Hypertension. 2025 Jan;82(1):84-95. doi: 10.1161/HYPERTENSIONAHA.124.23196 PMID: 38826318 Free PMC article. Updated. Preprint.

2

Clinical Relevance and Role of Neuronal AT₁ Receptors in ADAM17-Mediated ACE2 Shedding in Neurogenic Hypertension.

Xu J, Sriramula S, Xia H, Moreno-Walton L, Culicchia F, Domenig O, Poglitsch M, Lazartigues E. Xu J, et al. Circ Res. 2017 Jun 23;121(1):43-55. doi: 10.1161/CIRCRESAHA.116.310509. Epub 2017 May 16. Circ Res. 2017. PMID: 28512108 Free PMC article.

3

Excessive Glutamate Stimulation Impairs ACE2 Activity Through ADAM17-Mediated Shedding in Cultured Cortical Neurons.

Xu J, Sriramula S, Lazartigues E. Xu J, et al. Cell Mol Neurobiol. 2018 Aug;38(6):1235-1243. doi: 10.1007/s10571-018-0591-8. Epub 2018 May 15. Cell Mol Neurobiol. 2018. PMID: 29766392 Free PMC article.

4

Central administration of TRV027 improves baroreflex sensitivity and vascular reactivity in spontaneously hypertensive rats.

Carvalho-Galvão A, Ogunlade B, Xu J, Silva-Alves CRA, Mendes-Júnior LG, Guimarães DD, Cruz JC, Queiroz TM, Balarini CM, Braga VA, Filipeanu CM, Lazartigues E, de França-Silva MDS. Carvalho-Galvão A, et al. Among authors: xu j. Clin Sci (Lond). 2018 Jul 23;132(14):1513-1527. doi: 10.1042/CS20180222. Print 2018 Jul 31. Clin Sci (Lond). 2018. PMID: 29903768 Free PMC article.

5

Glutamatergic neurons of the paraventricular nucleus are critical contributors to the development of neurogenic hypertension.

Basting T, Xu J, Mukerjee S, Epling J, Fuchs R, Sriramula S, Lazartigues E. Basting T, et al. Among authors: xu j. J Physiol. 2018 Dec;596(24):6235-6248. doi: 10.1113/JP276229. Epub 2018 Sep 20. J Physiol. 2018. PMID: 30151830 Free PMC article.

6

Activation of ADAM17 (A Disintegrin and Metalloprotease 17) on Glutamatergic Neurons Selectively Promotes Sympathoexcitation.

Xu J, Molinas AJR, Mukerjee S, Morgan DA, Rahmouni K, Zsombok A, Lazartigues E. Xu J, et al. Hypertension. 2019 Jun;73(6):1266-1274. doi: 10.1161/HYPERTENSIONAHA.119.12832. Hypertension. 2019. PMID: 31006330 Free PMC article.

7

ACE2 and ADAM17 Interaction Regulates the Activity of Presympathetic Neurons.

Mukerjee S, Gao H, Xu J, Sato R, Zsombok A, Lazartigues E. Mukerjee S, et al. Among authors: xu j. Hypertension. 2019 Nov;74(5):1181-1191. doi: 10.1161/HYPERTENSIONAHA.119.13133. Epub 2019 Sep 30. Hypertension. 2019. PMID: 31564162 Free PMC article.

8

Effects of Chronic Nicotine Inhalation on Systemic and Pulmonary Blood Pressure and Right Ventricular Remodeling in Mice.

Oakes JM, Xu J, Morris TM, Fried ND, Pearson CS, Lobell TD, Gilpin NW, Lazartigues E, Gardner JD, Yue X. Oakes JM, et al. Among authors: xu j. Hypertension. 2020 May;75(5):1305-1314. doi: 10.1161/HYPERTENSIONAHA.119.14608. Epub 2020 Mar 16. Hypertension. 2020. PMID: 32172623 Free PMC article.

9

Expression of ACE2 in Human Neurons Supports the Neuro-Invasive Potential of COVID-19 Virus.

Xu J, Lazartigues E. Xu J, et al. Cell Mol Neurobiol. 2022 Jan;42(1):305-309. doi: 10.1007/s10571-020-00915-1. Epub 2020 Jul 4. Cell Mol Neurobiol. 2022. PMID: 32623546 Free PMC article.

10

Nedd4-2 up-regulation is associated with ACE2 ubiquitination in hypertension.

Mohammed M, Ogunlade B, Elgazzaz M, Berdasco C, Lakkappa N, Ghita I, Guidry JJ, Sriramula S, Xu J, Restivo L, Mendiola Plá MA, Bowles DE, Beyer AM, Yue X, Lazartigues E, Filipeanu CM. Mohammed M, et al. Among authors: xu j. Cardiovasc Res. 2023 Sep 5;119(11):2130-2141. doi: 10.1093/cvr/cvad070. Cardiovasc Res. 2023. PMID: 37161607 Free PMC article.

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