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Range of the perfluorooctanoate (PFOA) safe dose for human health: An international collaboration.
Burgoon LD, Clewell HJ, Cox T, Dekant W, Dell LD, Deyo JA, Dourson ML, Gadagbui BK, Goodrum P, Green LC, Vijayavel K, Kline TR, House-Knight T, Luster MI, Manning T, Nathanail P, Pagone F, Richardson K, Severo-Peixe T, Sharma A, Smith JS, Verma N, Wright J. Burgoon LD, et al. Among authors: clewell hj. Regul Toxicol Pharmacol. 2023 Dec;145:105502. doi: 10.1016/j.yrtph.2023.105502. Epub 2023 Oct 29. Regul Toxicol Pharmacol. 2023. PMID: 38832926
Evaluation of the validity of a perfluorooctane sulfonic acid exposure reconstruction using a measured serum concentration among workers with a wide range of exposure.
Campbell JL Jr, Linakis MW, Porter AK, Rosen EM, Logan PW, Kleinschmidt SE, Andres KL, Chang S, Taiwo OA, Olsen GW, Clewell HJ 3rd, Longnecker MP. Campbell JL Jr, et al. Among authors: clewell hj 3rd. Ann Work Expo Health. 2024 Dec 19:wxae099. doi: 10.1093/annweh/wxae099. Online ahead of print. Ann Work Expo Health. 2024. PMID: 39699232
Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene.
Campbell JL Jr, Clewell HJ 3rd, Van Landingham C, Gentry PR, Andersen ME. Campbell JL Jr, et al. Among authors: clewell hj 3rd. Front Pharmacol. 2023 Aug 17;14:1223808. doi: 10.3389/fphar.2023.1223808. eCollection 2023. Front Pharmacol. 2023. PMID: 37663267 Free PMC article.
Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation.
Moreau M, Mallick P, Smeltz M, Haider S, Nicolas CI, Pendse SN, Leonard JA, Linakis MW, McMullen PD, Clewell RA, Clewell HJ, Yoon M. Moreau M, et al. Among authors: clewell hj. Front Toxicol. 2022 Apr 29;4:894569. doi: 10.3389/ftox.2022.894569. eCollection 2022. Front Toxicol. 2022. PMID: 35573278 Free PMC article. Review.
240 results