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A high-density microfluidic bioreactor for the automated manufacturing of CAR T cells.
Sin WX, Jagannathan NS, Teo DBL, Kairi F, Fong SY, Tan JHL, Sandikin D, Cheung KW, Luah YH, Wu X, Raymond JJ, Lim FLWI, Lee YH, Seng MS, Soh SY, Chen Q, Ram RJ, Tucker-Kellogg L, Birnbaum ME. Sin WX, et al. Among authors: birnbaum me. Nat Biomed Eng. 2024 Dec;8(12):1571-1591. doi: 10.1038/s41551-024-01219-1. Epub 2024 Jun 4. Nat Biomed Eng. 2024. PMID: 38834752
Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains.
Gordon KS, Kyung T, Perez CR, Holec PV, Ramos A, Zhang AQ, Agarwal Y, Liu Y, Koch CE, Starchenko A, Joughin BA, Lauffenburger DA, Irvine DJ, Hemann MT, Birnbaum ME. Gordon KS, et al. Among authors: birnbaum me. Nat Biomed Eng. 2022 Jul;6(7):855-866. doi: 10.1038/s41551-022-00896-0. Epub 2022 Jun 16. Nat Biomed Eng. 2022. PMID: 35710755 Free PMC article.
Author Correction: Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains.
Gordon KS, Kyung T, Perez CR, Holec PV, Ramos A, Zhang AQ, Agarwal Y, Liu Y, Koch CE, Starchenko A, Joughin BA, Lauffenburger DA, Irvine DJ, Hemann MT, Birnbaum ME. Gordon KS, et al. Among authors: birnbaum me. Nat Biomed Eng. 2023 Apr;7(4):599-602. doi: 10.1038/s41551-023-01006-4. Nat Biomed Eng. 2023. PMID: 36737667 No abstract available.
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening.
Ramos A, Koch CE, Liu-Lupo Y, Hellinger RD, Kyung T, Abbott KL, Fröse J, Goulet D, Gordon KS, Eidell KP, Leclerc P, Whittaker CA, Larson RC, Muscato AJ, Yates KB, Dubrot J, Doench JG, Regev A, Vander Heiden MG, Maus MV, Manguso RT, Birnbaum ME, Hemann MT. Ramos A, et al. Among authors: birnbaum me. Nat Commun. 2023 Dec 5;14(1):8048. doi: 10.1038/s41467-023-43790-2. Nat Commun. 2023. PMID: 38052854 Free PMC article.
A synthetic scaffold to target peptide-MHC complexes.
Balivada PA, Gaglione SA, Birnbaum ME. Balivada PA, et al. Among authors: birnbaum me. Nat Biotechnol. 2024 Dec 13. doi: 10.1038/s41587-024-02513-8. Online ahead of print. Nat Biotechnol. 2024. PMID: 39672952 No abstract available.
Tuning up T-cell receptors.
Rappazzo CG, Birnbaum ME. Rappazzo CG, et al. Among authors: birnbaum me. Nat Biotechnol. 2017 Dec;35(12):1145-1146. doi: 10.1038/nbt.4009. Epub 2017 Nov 6. Nat Biotechnol. 2017. PMID: 29106406 No abstract available.
58 results