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Metabolomics Simultaneously Derives Benchmark Dose Estimates and Discovers Metabolic Biotransformations in a Rat Bioassay.
Sostare E, Bowen TJ, Lawson TN, Freier A, Li X, Lloyd GR, Najdekr L, Jankevics A, Smith T, Varshavi D, Ludwig C, Colbourne JK, Weber RJM, Crizer DM, Auerbach SS, Bucher JR, Viant MR. Sostare E, et al. Among authors: ludwig c. Chem Res Toxicol. 2024 Jun 17;37(6):923-934. doi: 10.1021/acs.chemrestox.4c00002. Epub 2024 Jun 6. Chem Res Toxicol. 2024. PMID: 38842447 Free PMC article.
Development of compact transcriptional effectors using high-throughput measurements in diverse contexts.
Tycko J, Van MV, Aradhana, DelRosso N, Ye H, Yao D, Valbuena R, Vaughan-Jackson A, Xu X, Ludwig C, Spees K, Liu K, Gu M, Khare V, Mukund AX, Suzuki PH, Arana S, Zhang C, Du PP, Ornstein TS, Hess GT, Kamber RA, Qi LS, Khalil AS, Bintu L, Bassik MC. Tycko J, et al. Among authors: ludwig c. Nat Biotechnol. 2024 Nov 1. doi: 10.1038/s41587-024-02442-6. Online ahead of print. Nat Biotechnol. 2024. PMID: 39487265
829 results