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Page 1
Imaging α-synuclein pathologies in animal models and patients with Parkinson's and related diseases.
Endo H, Ono M, Takado Y, Matsuoka K, Takahashi M, Tagai K, Kataoka Y, Hirata K, Takahata K, Seki C, Kokubo N, Fujinaga M, Mori W, Nagai Y, Mimura K, Kumata K, Kikuchi T, Shimozawa A, Mishra SK, Yamaguchi Y, Shimizu H, Kakita A, Takuwa H, Shinotoh H, Shimada H, Kimura Y, Ichise M, Suhara T, Minamimoto T, Sahara N, Kawamura K, Zhang MR, Hasegawa M, Higuchi M. Endo H, et al. Among authors: shinotoh h. Neuron. 2024 Aug 7;112(15):2540-2557.e8. doi: 10.1016/j.neuron.2024.05.006. Epub 2024 Jun 5. Neuron. 2024. PMID: 38843838 Free article.
An optimized reference tissue method for quantification of tau protein depositions in diverse neurodegenerative disorders by PET with 18F-PM-PBB3 (18F-APN-1607).
Tagai K, Ikoma Y, Endo H, Debnath OB, Seki C, Matsuoka K, Matsumoto H, Oya M, Hirata K, Shinotoh H, Takahata K, Kurose S, Sano Y, Ono M, Shimada H, Kawamura K, Zhang MR, Takado Y, Higuchi M. Tagai K, et al. Among authors: shinotoh h. Neuroimage. 2022 Dec 1;264:119763. doi: 10.1016/j.neuroimage.2022.119763. Epub 2022 Nov 24. Neuroimage. 2022. PMID: 36427751 Free article.
Two pathways differentially linking tau depositions, oxidative stress, and neuronal loss to apathetic phenotypes in progressive supranuclear palsy.
Matsuoka K, Takado Y, Tagai K, Kubota M, Sano Y, Takahata K, Ono M, Seki C, Matsumoto H, Endo H, Shinotoh H, Sahara Y, Obata T, Near J, Kawamura K, Zhang MR, Suhara T, Shimada H, Higuchi M. Matsuoka K, et al. Among authors: shinotoh h. J Neurol Sci. 2023 Jan 15;444:120514. doi: 10.1016/j.jns.2022.120514. Epub 2022 Dec 1. J Neurol Sci. 2023. PMID: 36473346 Free article.
Investigating neural dysfunction with abnormal protein deposition in Alzheimer's disease through magnetic resonance spectroscopic imaging, plasma biomarkers, and positron emission tomography.
Matsuoka K, Hirata K, Kokubo N, Maeda T, Tagai K, Endo H, Takahata K, Shinotoh H, Ono M, Seki C, Tatebe H, Kawamura K, Zhang MR, Shimada H, Tokuda T, Higuchi M, Takado Y. Matsuoka K, et al. Among authors: shinotoh h. Neuroimage Clin. 2024;41:103560. doi: 10.1016/j.nicl.2023.103560. Epub 2023 Dec 22. Neuroimage Clin. 2024. PMID: 38147791 Free PMC article.
Polygenic effects on the risk of Alzheimer's disease in the Japanese population.
Kikuchi M, Miyashita A, Hara N, Kasuga K, Saito Y, Murayama S, Kakita A, Akatsu H, Ozaki K, Niida S, Kuwano R, Iwatsubo T, Nakaya A, Ikeuchi T; Alzheimer’s Disease Neuroimaging Initiative; Japanese Alzheimer’s Disease Neuroimaging Initiative. Kikuchi M, et al. Alzheimers Res Ther. 2024 Feb 27;16(1):45. doi: 10.1186/s13195-024-01414-x. Alzheimers Res Ther. 2024. PMID: 38414085 Free PMC article.
In vivo PET classification of tau pathologies in patients with frontotemporal dementia.
Kubota M, Endo H, Takahata K, Tagai K, Suzuki H, Onaya M, Sano Y, Yamamoto Y, Kurose S, Matsuoka K, Seki C, Shinotoh H, Kawamura K, Zhang MR, Takado Y, Shimada H, Higuchi M. Kubota M, et al. Among authors: shinotoh h. Brain Commun. 2024 Mar 1;6(2):fcae075. doi: 10.1093/braincomms/fcae075. eCollection 2024. Brain Commun. 2024. PMID: 38510212 Free PMC article.
In Vivo Assessment of Astrocyte Reactivity in Patients with Progressive Supranuclear Palsy.
Hirata K, Matsuoka K, Tagai K, Endo H, Tatebe H, Ono M, Kokubo N, Kataoka Y, Oyama A, Shinotoh H, Takahata K, Obata T, Dehghani M, Near J, Kawamura K, Zhang MR, Shimada H, Shimizu H, Kakita A, Yokota T, Tokuda T, Higuchi M, Takado Y. Hirata K, et al. Among authors: shinotoh h. Ann Neurol. 2024 Aug;96(2):247-261. doi: 10.1002/ana.26962. Epub 2024 May 21. Ann Neurol. 2024. PMID: 38771066
A novel plasma p-tau181 assay as a specific biomarker of tau pathology in Alzheimer's disease.
Tagai K, Tatebe H, Matsuura S, Hong Z, Kokubo N, Matsuoka K, Endo H, Oyama A, Hirata K, Shinotoh H, Kataoka Y, Matsumoto H, Oya M, Kurose S, Takahata K, Ichihashi M, Kubota M, Seki C, Shimada H, Takado Y, Kawamura K, Zhang MR, Soeda Y, Takashima A, Higuchi M, Tokuda T. Tagai K, et al. Among authors: shinotoh h. Transl Neurodegener. 2024 Sep 3;13(1):44. doi: 10.1186/s40035-024-00439-4. Transl Neurodegener. 2024. PMID: 39238067 Free PMC article. No abstract available.
Distinct tau pathologies in the nucleus basalis of Meynert between early-onset and late-onset Alzheimer's disease patients revealed by positron emission tomography.
Suzuki H, Tagai K, Ono M, Shimizu H, Endo H, Matsumoto H, Kubota M, Kataoka Y, Moriguchi S, Kurose S, Ichihashi M, Shinotoh H, Matsuoka K, Kokubo N, Tatebe H, Matsuura S, Yamamoto Y, Momota Y, Kawamura K, Zhang MR, Takado Y, Shimada H, Tokuda T, Onaya M, Mimura M, Kakita A, Sahara N, Uchida H, Higuchi M, Takahata K. Suzuki H, et al. Among authors: shinotoh h. J Alzheimers Dis. 2024 Dec;102(4):1271-1285. doi: 10.1177/13872877241297382. Epub 2024 Nov 11. J Alzheimers Dis. 2024. PMID: 39529384
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer's disease patients.
Kondo T, Hara N, Koyama S, Yada Y, Tsukita K, Nagahashi A, Ikeuchi T, Ishii K, Asada T, Arai T, Yamada R; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Japanese Alzheimer’s Disease Neuroimaging Initiative (J-ADNI); Inoue H. Kondo T, et al. Nat Aging. 2022 Feb;2(2):125-139. doi: 10.1038/s43587-021-00158-9. Epub 2022 Feb 17. Nat Aging. 2022. PMID: 37117761
132 results