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Page 1
Chemical synthesis of grafted cyclotides using a "plug and play" approach.
Koehbach J, Muratspahić E, Ahmed ZM, White AM, Tomašević N, Durek T, Clark RJ, Gruber CW, Craik DJ. Koehbach J, et al. Among authors: gruber cw. RSC Chem Biol. 2024 Apr 29;5(6):567-571. doi: 10.1039/d4cb00008k. eCollection 2024 Jun 5. RSC Chem Biol. 2024. PMID: 38846076 Free PMC article.
Harnessing cyclotides to design and develop novel peptide GPCR ligands.
Muratspahić E, Koehbach J, Gruber CW, Craik DJ. Muratspahić E, et al. Among authors: gruber cw. RSC Chem Biol. 2020 Jul 22;1(4):177-191. doi: 10.1039/d0cb00062k. eCollection 2020 Oct 1. RSC Chem Biol. 2020. PMID: 34458757 Free PMC article. Review.
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.
Koehbach J, O'Brien M, Muttenthaler M, Miazzo M, Akcan M, Elliott AG, Daly NL, Harvey PJ, Arrowsmith S, Gunasekera S, Smith TJ, Wray S, Göransson U, Dawson PE, Craik DJ, Freissmuth M, Gruber CW. Koehbach J, et al. Among authors: gruber cw. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21183-8. doi: 10.1073/pnas.1311183110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248349 Free PMC article.
From ethnopharmacology to drug design.
Koehbach J, Gruber CW. Koehbach J, et al. Among authors: gruber cw. Commun Integr Biol. 2013 Nov 1;6(6):e27583. doi: 10.4161/cib.27583. Epub 2014 Jan 8. Commun Integr Biol. 2013. PMID: 24567782 Free PMC article.
Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain.
Muratspahić E, Tomašević N, Koehbach J, Duerrauer L, Hadžić S, Castro J, Schober G, Sideromenos S, Clark RJ, Brierley SM, Craik DJ, Gruber CW. Muratspahić E, et al. Among authors: gruber cw. J Med Chem. 2021 Jul 8;64(13):9042-9055. doi: 10.1021/acs.jmedchem.1c00158. Epub 2021 Jun 23. J Med Chem. 2021. PMID: 34162205 Free PMC article.
Plant-Derived Cyclotides Modulate κ-Opioid Receptor Signaling.
Muratspahić E, Tomašević N, Nasrollahi-Shirazi S, Gattringer J, Emser FS, Freissmuth M, Gruber CW. Muratspahić E, et al. Among authors: gruber cw. J Nat Prod. 2021 Aug 27;84(8):2238-2248. doi: 10.1021/acs.jnatprod.1c00301. Epub 2021 Jul 26. J Nat Prod. 2021. PMID: 34308635 Free PMC article.
107 results