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RET overexpression leads to increased brain metastatic competency in luminal breast cancer.
Jagust P, Powell AM, Ola M, Watson L, de Pablos-Aragoneses A, García-Gómez P, Fallon R, Bane F, Heiland M, Morris G, Cavanagh B, McGrath J, Ottaviani D, Hegarty A, Cocchiglia S, Sweeney KJ, MacNally S, Brett FM, Cryan J, Beausang A, Morris P, Valiente M, Hill ADK, Varešlija D, Young LS. Jagust P, et al. Among authors: vareslija d. J Natl Cancer Inst. 2024 Oct 1;116(10):1632-1644. doi: 10.1093/jnci/djae091. J Natl Cancer Inst. 2024. PMID: 38852945 Free PMC article.
Transcriptomic Profiling of Sequential Tumors from Breast Cancer Patients Provides a Global View of Metastatic Expression Changes Following Endocrine Therapy.
McBryan J, Fagan A, McCartan D, Bane FT, Varešlija D, Cocchiglia S, Byrne C, Bolger J, McIlroy M, Hudson L, Tibbitts P, Gaora PÓ, Hill AD, Young LS. McBryan J, et al. Among authors: vareslija d. Clin Cancer Res. 2015 Dec 1;21(23):5371-9. doi: 10.1158/1078-0432.CCR-14-2155. Epub 2015 Aug 3. Clin Cancer Res. 2015. PMID: 26240272
Patient-Derived Xenografts of Breast Cancer.
Varešlija D, Cocchiglia S, Byrne C, Young L. Varešlija D, et al. Methods Mol Biol. 2017;1501:327-336. doi: 10.1007/978-1-4939-6475-8_17. Methods Mol Biol. 2017. PMID: 27796962
Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets.
Varešlija D, Priedigkeit N, Fagan A, Purcell S, Cosgrove N, O'Halloran PJ, Ward E, Cocchiglia S, Hartmaier R, Castro CA, Zhu L, Tseng GC, Lucas PC, Puhalla SL, Brufsky AM, Hamilton RL, Mathew A, Leone JP, Basudan A, Hudson L, Dwyer R, Das S, O'Connor DP, Buckley PG, Farrell M, Hill ADK, Oesterreich S, Lee AV, Young LS. Varešlija D, et al. J Natl Cancer Inst. 2019 Apr 1;111(4):388-398. doi: 10.1093/jnci/djy110. J Natl Cancer Inst. 2019. PMID: 29961873 Free PMC article.
ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis.
Charmsaz S, Doherty B, Cocchiglia S, Varešlija D, Marino A, Cosgrove N, Marques R, Priedigkeit N, Purcell S, Bane F, Bolger J, Byrne C, O'Halloran PJ, Brett F, Sheehan K, Brennan K, Hopkins AM, Keelan S, Jagust P, Madden S, Martinelli C, Battaglini M, Oesterreich S, Lee AV, Ciofani G, Hill ADK, Young LS. Charmsaz S, et al. Among authors: vareslija d. BMC Med. 2020 Nov 19;18(1):349. doi: 10.1186/s12916-020-01806-4. BMC Med. 2020. PMID: 33208158 Free PMC article.
Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phenotype.
Varešlija D, Ward E, Purcell SP, Cosgrove NS, Cocchiglia S, O'Halloran PJ, Charmsaz S, Bane FT, Brett FM, Farrell M, Cryan J, Beausang A, Hudson L, Turnbul AK, Dixon JM, Hill ADK, Priedigkeit N, Oesterreich S, Lee AV, Sims AH, Redmond AM, Carroll JS, Young LS. Varešlija D, et al. Oncogene. 2021 Feb;40(7):1318-1331. doi: 10.1038/s41388-020-01606-3. Epub 2021 Jan 8. Oncogene. 2021. PMID: 33420368 Free PMC article.
31 results