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Cell surface CD55 traffics to the nucleus leading to cisplatin resistance and stemness by inducing PRC2 and H3K27 trimethylation on chromatin in ovarian cancer.
Bharti R, Dey G, Khan D, Myers A, Huffman OG, Saygin C, Braley C, Richards E, Sangwan N, Willard B, Lathia JD, Fox PL, Lin F, Jha BK, Brown JM, Yu JS, Dwidar M, Joehlin-Price A, Vargas R, Michener CM, Longworth MS, Reizes O. Bharti R, et al. Among authors: brown jm. Mol Cancer. 2024 Jun 10;23(1):121. doi: 10.1186/s12943-024-02028-5. Mol Cancer. 2024. PMID: 38853277 Free PMC article.
Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver Disease.
Chen T, Dalton G, Oh SH, Maeso-Diaz R, Du K, Meyers RA, Guy C, Abdelmalek MF, Henao R, Guarnieri P, Pullen SS, Gregory S, Locker J, Brown JM, Diehl AM. Chen T, et al. Among authors: brown jm. Cell Mol Gastroenterol Hepatol. 2023;15(4):949-970. doi: 10.1016/j.jcmgh.2022.12.008. Epub 2022 Dec 16. Cell Mol Gastroenterol Hepatol. 2023. PMID: 36535507 Free PMC article.
Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice.
Zelows MM, Cady C, Dharanipragada N, Mead AE, Kipp ZA, Bates EA, Varadharajan V, Banerjee R, Park SH, Shelman NR, Clarke HA, Hawkinson TR, Medina T, Sun RC, Lydic TA, Hinds TD Jr, Brown JM, Softic S, Graf GA, Helsley RN. Zelows MM, et al. Among authors: brown jm. Mol Metab. 2023 Dec;78:101815. doi: 10.1016/j.molmet.2023.101815. Epub 2023 Oct 4. Mol Metab. 2023. PMID: 37797918 Free PMC article.
Creeping Fat-Derived Free Fatty Acids Induce Hyperplasia of Intestinal Muscularis Propria Muscle Cells: A Novel Link Between Fat and Intestinal Stricture Formation in Crohn's Disease.
Liu W, Mao R, Nga Le TH, West G, Varadharajan V, Banerjee R, Doyon G, Mukherjee P, Nguyen QT, Mulya A, Rennison JH, Gordon IO, Cruise M, Hu S, Czarnecki D, Plesec T, Chandra J, Banerjee S, Wang J, Massey WJ, Goren I, Lin SN, Kurada S, Cohen BL, Qazi T, Holubar SD, Lipman J, Kanters A, Gliniak CM, Scherer PE, Chen MH, Siegmund B, Ivanov AI, Fiocchi C, Van Wagoner DR, Brown JM, Rieder F. Liu W, et al. Among authors: brown jm. Gastroenterology. 2024 Nov 8:S0016-5085(24)05659-2. doi: 10.1053/j.gastro.2024.10.034. Online ahead of print. Gastroenterology. 2024. PMID: 39522890
Effects of fixation on tissues.
Mortensen E, Brown JM. Mortensen E, et al. Among authors: brown jm. Methods Mol Med. 2003;81:163-79. doi: 10.1385/1-59259-372-0:163. Methods Mol Med. 2003. PMID: 12725120 No abstract available.
Characterisation of the HollandPTC R&D proton beamline for physics and radiobiology studies.
Rovituso M, Groenendijk CF, van der Wal E, van Burik W, Ibrahimi A, Rituerto Prieto H, Brown JMC, Weber U, Simeonov Y, Fontana M, Lathouwers D, van Vulpen M, Hoogeman M. Rovituso M, et al. Among authors: brown jmc. Phys Med. 2025 Jan 7;130:104883. doi: 10.1016/j.ejmp.2024.104883. Online ahead of print. Phys Med. 2025. PMID: 39778326
Alcohol-induced gut microbial reorganization and associated overproduction of phenylacetylglutamine promotes cardiovascular disease.
Li Z, Gu M, Zaparte A, Fu X, Mahen K, Mrdjen M, Li XS, Yang Z, Ma J, Thoudam T, Chandler K, Hesler M, Heathers L, Gorse K, Van TT, Wong D, Gibson AM, Wang Z, Taylor CM, Quijada P, Makarewich CA, Hazen SL, Liangpunsakul S, Brown JM, Lefer DJ, Welsh DA, Sharp TE 3rd. Li Z, et al. Among authors: brown jm. Nat Commun. 2024 Dec 30;15(1):10788. doi: 10.1038/s41467-024-55084-2. Nat Commun. 2024. PMID: 39738016 Free PMC article.
Venous Endothelial Cell Transcriptomic Profiling Implicates METAP1 in Preeclampsia.
Pabon MA, Weisbrod RM, Castro C, Li H, Xia P, Kang J, Ardissino M, Economy KE, Yang Z, Shi Y, Kim E, Perillo A, Barrett L, Brown JM, Divakaran S, Cetinbas M, Sadreyev RI, de Marvao A, Wood MJ, Scott NS, Lau ES, Ho JE, Di Carli MF, Roh JD, Hamburg NM, Honigberg MC. Pabon MA, et al. Among authors: brown jm. Circ Res. 2024 Dec 27. doi: 10.1161/CIRCRESAHA.124.324606. Online ahead of print. Circ Res. 2024. PMID: 39727051
Characterizing the Origins of Primary Aldosteronism.
Brown JM, Honzel B, Tsai LC, Milks J, Neibuhr Y, Newman AJ, Cherney M, Stouffer D, Auchus RJ, Vaidya A. Brown JM, et al. Hypertension. 2024 Dec 11. doi: 10.1161/HYPERTENSIONAHA.124.24153. Online ahead of print. Hypertension. 2024. PMID: 39660429
2,120 results