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Cell surface CD55 traffics to the nucleus leading to cisplatin resistance and stemness by inducing PRC2 and H3K27 trimethylation on chromatin in ovarian cancer.
Bharti R, Dey G, Khan D, Myers A, Huffman OG, Saygin C, Braley C, Richards E, Sangwan N, Willard B, Lathia JD, Fox PL, Lin F, Jha BK, Brown JM, Yu JS, Dwidar M, Joehlin-Price A, Vargas R, Michener CM, Longworth MS, Reizes O. Bharti R, et al. Among authors: michener cm. Mol Cancer. 2024 Jun 10;23(1):121. doi: 10.1186/s12943-024-02028-5. Mol Cancer. 2024. PMID: 38853277 Free PMC article.
CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors.
Saygin C, Wiechert A, Rao VS, Alluri R, Connor E, Thiagarajan PS, Hale JS, Li Y, Chumakova A, Jarrar A, Parker Y, Lindner DJ, Nagaraj AB, Kim JJ, DiFeo A, Abdul-Karim FW, Michener C, Rose PG, DeBernardo R, Mahdi H, McCrae KR, Lin F, Lathia JD, Reizes O. Saygin C, et al. J Exp Med. 2017 Sep 4;214(9):2715-2732. doi: 10.1084/jem.20170438. Epub 2017 Aug 24. J Exp Med. 2017. PMID: 28838952 Free PMC article.
Thy-1 predicts poor prognosis and is associated with self-renewal in ovarian cancer.
Connor EV, Saygin C, Braley C, Wiechert AC, Karunanithi S, Crean-Tate K, Abdul-Karim FW, Michener CM, Rose PG, Lathia JD, Reizes O. Connor EV, et al. Among authors: michener cm. J Ovarian Res. 2019 Nov 17;12(1):112. doi: 10.1186/s13048-019-0590-5. J Ovarian Res. 2019. PMID: 31735168 Free PMC article.
100 results