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Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor.
Johannes JW, Balazs AYS, Barratt D, Bista M, Chuba MD, Cosulich S, Critchlow SE, Degorce SL, Di Fruscia P, Edmondson SD, Embrey KJ, Fawell S, Ghosh A, Gill SJ, Gunnarsson A, Hande SM, Heightman TD, Hemsley P, Illuzzi G, Lane J, Larner CJB, Leo E, Liu L, Madin A, McWilliams L, O'Connor MJ, Orme JP, Pachl F, Packer MJ, Pei X, Pike A, Schimpl M, She H, Staniszewska AD, Talbot V, Underwood E, Varnes JG, Xue L, Yao T, Zhang K, Zhang AX, Zheng X. Johannes JW, et al. Among authors: o connor mj. J Med Chem. 2024 Dec 26;67(24):21717-21728. doi: 10.1021/acs.jmedchem.4c01725. Epub 2024 Dec 10. J Med Chem. 2024. PMID: 39655996
Negative Pressure Wound Therapy with Instillation for Periprosthetic Infection after Breast Reconstruction: A Systematic Review.
O'Connor MJ, Huffman KN, Ho K, Marzouk S, Casas Fuentes RJ, Zhang KL, Melnick BA, Sparks PJ, Harris R, Bartler AV, Collinsworth A, Griffin L, Galiano RD. O'Connor MJ, et al. Plast Reconstr Surg Glob Open. 2024 Nov 5;12(11):e6267. doi: 10.1097/GOX.0000000000006267. eCollection 2024 Nov. Plast Reconstr Surg Glob Open. 2024. PMID: 39507314 Free PMC article.
Adavosertib in Combination with Olaparib in Patients with Refractory Solid Tumors: An Open-Label, Dose-Finding, and Dose-Expansion Phase Ib Trial.
Hamilton EP, Falchook GS, Wang JS, Fu S, Oza AM, Imedio ER, Kumar S, Ottesen L, Mugundu GM, de Bruin EC, O'Connor MJ, Jones SF, Spigel DR, Li BT. Hamilton EP, et al. Among authors: o connor mj. Target Oncol. 2024 Nov;19(6):879-892. doi: 10.1007/s11523-024-01102-8. Epub 2024 Nov 1. Target Oncol. 2024. PMID: 39487373 Free PMC article. Clinical Trial.
ACTION-ARC Pediatric and Adult Congenital Heart Disease Ventricular Assist Device Adverse Event Definitions-2023.
Lorts A, VanderPluym C, Adachi I, Perry T, Alexander PMA, Almond CS, Auerbach SR, Barbaro RP, Bhavsar S, Bourque K, Conway J, Danziger-Isakov LA, Davies RR, Eghtesady P, Hirata Y, Ichord RN, Kormos RL, Kroslowitz R, Krucoff M, Lantz J, Mehegan M, Mehran R, Morales DLS, Murray J, Niebler RA, O'Connor MJ, Pagani FD, Peng DM, Rossano JW, Spitzer E, Steiner ME, Sutcliffe DL, Taylor JM, Villa CR, Wearden PD, Rosenthal D. Lorts A, et al. Among authors: o connor mj. ASAIO J. 2024 Nov 1;70(11):911-919. doi: 10.1097/MAT.0000000000002288. Epub 2024 Sep 27. ASAIO J. 2024. PMID: 39330959
463 results