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Microarray identifies extensive downregulation of noncollagen extracellular matrix and profibrotic growth factor genes in chronic isolated mitral regurgitation in the dog.
Zheng J, Chen Y, Pat B, Dell'italia LA, Tillson M, Dillon AR, Powell PC, Shi K, Shah N, Denney T, Husain A, Dell'Italia LJ. Zheng J, et al. Among authors: pat b. Circulation. 2009 Apr 21;119(15):2086-95. doi: 10.1161/CIRCULATIONAHA.108.826230. Epub 2009 Apr 6. Circulation. 2009. PMID: 19349319 Free PMC article.
Chymase inhibition prevents fibronectin and myofibrillar loss and improves cardiomyocyte function and LV torsion angle in dogs with isolated mitral regurgitation.
Pat B, Chen Y, Killingsworth C, Gladden JD, Shi K, Zheng J, Powell PC, Walcott G, Ahmed MI, Gupta H, Desai R, Wei CC, Hase N, Kobayashi T, Sabri A, Granzier H, Denney T, Tillson M, Dillon AR, Husain A, Dell'italia LJ. Pat B, et al. Circulation. 2010 Oct 12;122(15):1488-95. doi: 10.1161/CIRCULATIONAHA.109.921619. Epub 2010 Sep 27. Circulation. 2010. PMID: 20876440 Free PMC article.
Loss of interstitial collagen causes structural and functional alterations of cardiomyocyte subsarcolemmal mitochondria in acute volume overload.
Ulasova E, Gladden JD, Chen Y, Zheng J, Pat B, Bradley W, Powell P, Zmijewski JW, Zelickson BR, Ballinger SW, Darley-Usmar V, Dell'italia LJ. Ulasova E, et al. Among authors: pat b. J Mol Cell Cardiol. 2011 Jan;50(1):147-56. doi: 10.1016/j.yjmcc.2010.10.034. Epub 2010 Nov 6. J Mol Cell Cardiol. 2011. PMID: 21059354 Free PMC article.
Dynamic molecular and histopathological changes in the extracellular matrix and inflammation in the transition to heart failure in isolated volume overload.
Chen YW, Pat B, Gladden JD, Zheng J, Powell P, Wei CC, Cui X, Husain A, Dell'italia LJ. Chen YW, et al. Among authors: pat b. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2251-60. doi: 10.1152/ajpheart.01104.2010. Epub 2011 Mar 18. Am J Physiol Heart Circ Physiol. 2011. PMID: 21421827 Free PMC article.
O-GlcNAcylation, novel post-translational modification linking myocardial metabolism and cardiomyocyte circadian clock.
Durgan DJ, Pat BM, Laczy B, Bradley JA, Tsai JY, Grenett MH, Ratcliffe WF, Brewer RA, Nagendran J, Villegas-Montoya C, Zou C, Zou L, Johnson RL Jr, Dyck JR, Bray MS, Gamble KL, Chatham JC, Young ME. Durgan DJ, et al. Among authors: pat bm. J Biol Chem. 2011 Dec 30;286(52):44606-19. doi: 10.1074/jbc.M111.278903. Epub 2011 Nov 8. J Biol Chem. 2011. PMID: 22069332 Free PMC article.
47 results