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Pilot study to evaluate the use of remote patient monitoring to guide the timing of valve intervention in patients with severe asymptomatic aortic stenosis (APRAISE-AS): study protocol for a randomised controlled trial delivered in two tertiary cardiac centres in the UK.
Khan N, Steeds RP, Kyte D, Fabritz L, Collis P, Chua W, Stubbs C, Mehta S, Sun Y, Nulty M, Kirkham K, Cotton JM. Khan N, et al. Among authors: stubbs c. BMJ Open. 2024 Jun 10;14(6):e086587. doi: 10.1136/bmjopen-2024-086587. BMJ Open. 2024. PMID: 38858149 Free PMC article.
Effectiveness and cost-effectiveness of Assets-based feeding help Before and After birth (ABA-feed) for improving breastfeeding initiation and continuation: protocol for a multicentre randomised controlled trial (Version 3.0).
Clarke J, Dombrowski SU, Gkini E, Hoddinott P, Ingram J, MacArthur C, Moss N, Ocansey L, Roberts T, Thomson G, Sanders J, Sitch AJ, Stubbs C, Taylor B, Tearne S, Woolley R, Jolly K. Clarke J, et al. Among authors: stubbs c. BMJ Open. 2023 Nov 15;13(11):e075460. doi: 10.1136/bmjopen-2023-075460. BMJ Open. 2023. PMID: 37968005 Free PMC article.
Ulipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding (UCON): a randomised controlled phase III trial.
Whitaker LHR, Middleton LJ, Daniels JP, Williams ARW, Priest L, Odedra S, Cheed V, Stubbs CE, Clark TJ, Lumsden MA, Hapangama DK, Bhattacharya S, Smith PP, Nicholls EP, Roberts N, Semple SI, Saraswat L, Walker J, Chodankar RR, Critchley HOD; UCON Collaborative. Whitaker LHR, et al. EClinicalMedicine. 2023 May 18;60:101995. doi: 10.1016/j.eclinm.2023.101995. eCollection 2023 Jun. EClinicalMedicine. 2023. PMID: 37251622 Free PMC article.
Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage.
Toader AM, Campbell MK, Quint JK, Robling M, Sydes MR, Thorn J, Wright-Hughes A, Yu LM, Abbott TEF, Bond S, Caskey FJ, Clout M, Collinson M, Copsey B, Davies G, Driscoll T, Gamble C, Griffin XL, Hamborg T, Harris J, Harrison DA, Harji D, Henderson EJ, Logan P, Love SB, Magee LA, O'Brien A, Pufulete M, Ramnarayan P, Saratzis A, Smith J, Solis-Trapala I, Stubbs C, Farrin A, Williamson P. Toader AM, et al. Among authors: stubbs c. Trials. 2024 Jan 29;25(1):94. doi: 10.1186/s13063-024-07926-z. Trials. 2024. PMID: 38287428 Free PMC article.
Preventing recurrence of endometriosis-related pain by means of long-acting progestogen therapy: the PRE-EMPT RCT.
Cooper KG, Bhattacharya S, Daniels JP, Cheed V, Gennard L, Leighton L, Pirie D, Melyda M, Monahan M, Weckesser A, Roberts T, Denny E, Ocansey L, Stubbs C, Cox E, Jones G, Clark TJ, Saridogan E, Gupta JK, Critchley HO, Horne A, Middleton LJ. Cooper KG, et al. Among authors: stubbs c. Health Technol Assess. 2024 Sep;28(55):1-77. doi: 10.3310/SQWY6998. Health Technol Assess. 2024. PMID: 39259620 Free PMC article. Clinical Trial.
Cerclage suture type to prevent pregnancy loss in women requiring a vaginal cervical cerclage: the C-STICH RCT.
Hodgetts Morton V, Moakes CA, Daniels J, Middleton L, Shennan A, Brocklehurst P, Israfil-Bayli F, Ewer AK, Gray J, Simpson NA, Norman JE, Lees C, Tryposkiadis K, Stubbs C, Hughes M, Morris RK, Toozs-Hobson P. Hodgetts Morton V, et al. Among authors: stubbs c. Health Technol Assess. 2024 Aug;28(40):1-44. doi: 10.3310/YKTW8402. Health Technol Assess. 2024. PMID: 39239933 Free PMC article. Clinical Trial.
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity.
Smith JM, Barlaam B, Beattie D, Bradshaw L, Chan HM, Chiarparin E, Collingwood O, Cooke SL, Cronin A, Cumming I, Dean E, Debreczeni JÉ, Del Barco Barrantes I, Diene C, Gianni D, Guerot C, Guo X, Guven S, Hayhow TG, Hong T, Kemmitt PD, Lamont GM, Lamont S, Lynch JT, McWilliams L, Moore S, Raubo P, Robb GR, Robinson J, Scott JS, Srinivasan B, Steward O, Stubbs CJ, Syson K, Tan L, Turner O, Underwood E, Urosevic J, Vazquez-Chantada M, Whittaker AL, Wilson DM, Winter-Holt JJ. Smith JM, et al. Among authors: stubbs cj. J Med Chem. 2024 Aug 22;67(16):13604-13638. doi: 10.1021/acs.jmedchem.4c00097. Epub 2024 Jul 30. J Med Chem. 2024. PMID: 39080842
Fragment-Based Discovery of Novel MUS81 Inhibitors.
Collie GW, Börjesson U, Chen Y, Dong Z, Di Fruscia P, Gohlke A, Hoyle A, Hunt TA, Jesani MH, Luo H, Luptak J, Milbradt AG, Narasimhan P, Packer M, Patel S, Qiao J, Storer RI, Stubbs CJ, Tart J, Truman C, Wang AT, Wheeler MG, Winter-Holt J. Collie GW, et al. Among authors: stubbs cj. ACS Med Chem Lett. 2024 Jun 7;15(7):1151-1158. doi: 10.1021/acsmedchemlett.3c00453. eCollection 2024 Jul 11. ACS Med Chem Lett. 2024. PMID: 39015284 Free PMC article.
256 results