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Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress.
Chua V, Lopez-Anton M, Mizue Terai, Ryota Tanaka, Baqai U, Purwin TJ, Haj JI, Waltrich FJ Jr, Trachtenberg I, Luo K, Tudi R, Jeon A, Han A, Chervoneva I, Davies MA, Aguirre-Ghiso JA, Sato T, Aplin AE. Chua V, et al. Among authors: sato t. Sci Signal. 2024 Jun 11;17(840):eadn8376. doi: 10.1126/scisignal.adn8376. Epub 2024 Jun 11. Sci Signal. 2024. PMID: 38861613 Free PMC article.
Metabolic Adaptations to MEK and CDK4/6 Cotargeting in Uveal Melanoma.
Teh JLF, Purwin TJ, Han A, Chua V, Patel P, Baqai U, Liao C, Bechtel N, Sato T, Davies MA, Aguirre-Ghiso J, Aplin AE. Teh JLF, et al. Among authors: sato t. Mol Cancer Ther. 2020 Aug;19(8):1719-1726. doi: 10.1158/1535-7163.MCT-19-1016. Epub 2020 May 19. Mol Cancer Ther. 2020. PMID: 32430489 Free PMC article.
Effects of Oncogenic Gαq and Gα11 Inhibition by FR900359 in Uveal Melanoma.
Lapadula D, Farias E, Randolph CE, Purwin TJ, McGrath D, Charpentier TH, Zhang L, Wu S, Terai M, Sato T, Tall GG, Zhou N, Wedegaertner PB, Aplin AE, Aguirre-Ghiso J, Benovic JL. Lapadula D, et al. Among authors: sato t. Mol Cancer Res. 2019 Apr;17(4):963-973. doi: 10.1158/1541-7786.MCR-18-0574. Epub 2018 Dec 19. Mol Cancer Res. 2019. PMID: 30567972 Free PMC article.
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