El-Sayed SM - Search Results

1

Synthesis, molecular modeling simulations and anticancer activity of some new Imidazo[2,1-b]thiazole analogues as EGFR/HER2 and DHFR inhibitors.

Moharram EA, El-Sayed SM, Ghabbour HA, El-Subbagh HI. Moharram EA, et al. Among authors: el sayed sm. Bioorg Chem. 2024 Sep;150:107538. doi: 10.1016/j.bioorg.2024.107538. Epub 2024 Jun 6. Bioorg Chem. 2024. PMID: 38861913

2

New thiazolopyrimidine as anticancer agents: Synthesis, biological evaluation, DNA binding, molecular modeling and ADMET study.

Al-Rashood ST, Elshahawy SS, El-Qaias AM, El-Behedy DS, Hassanin AA, El-Sayed SM, El-Messery SM, Shaldam MA, Hassan GS. Al-Rashood ST, et al. Bioorg Med Chem Lett. 2020 Dec 1;30(23):127611. doi: 10.1016/j.bmcl.2020.127611. Epub 2020 Oct 14. Bioorg Med Chem Lett. 2020. PMID: 33068712

3

DNA binding studies of novel diazatruxenones analogs as potential anticancer agents: Synthesis, antitumor investigation, DNA binding, SAR and molecular modeling calculation.

El Sayed MT, Shabaan SN, Sarhan AE, El-Messery SM, El-Sayed SM, Hassan GS. El Sayed MT, et al. Bioorg Chem. 2020 Nov;104:104323. doi: 10.1016/j.bioorg.2020.104323. Epub 2020 Sep 30. Bioorg Chem. 2020. PMID: 33142430

4

Thiazole-based SARS-CoV-2 protease (COV M^pro ) inhibitors: Design, synthesis, enzyme inhibition, and molecular modeling simulations.

Elsayed RW, Sabry MA, El-Subbagh HI, Bayoumi SM, El-Sayed SM. Elsayed RW, et al. Arch Pharm (Weinheim). 2022 Sep;355(9):e2200121. doi: 10.1002/ardp.202200121. Epub 2022 May 23. Arch Pharm (Weinheim). 2022. PMID: 35607750 Free PMC article.

5

New phthalimide-based derivatives as EGFR-TK inhibitors: Synthesis, biological evaluation, and molecular modeling study.

Mansour NI, El-Sayed SM, El-Gohary NS, Abdel-Aziz NI, El-Subbagh HI, Ghaly MA. Mansour NI, et al. Bioorg Chem. 2022 Oct;127:105966. doi: 10.1016/j.bioorg.2022.105966. Epub 2022 Jun 14. Bioorg Chem. 2022. PMID: 35728294

6

Synthesis, biological evaluation, and molecular modeling studies of new benzoxazole derivatives as PARP-2 inhibitors targeting breast cancer.

El-Ghobashy NM, El-Sayed SM, Shehata IA, El-Ashmawy MB. El-Ghobashy NM, et al. Sci Rep. 2022 Sep 28;12(1):16246. doi: 10.1038/s41598-022-20260-1. Sci Rep. 2022. PMID: 36171229 Free PMC article.

7

Hydrazinecarbonyl-thiazol-2-acetamides with pronounced apoptotic behavior: synthesis, in vitro/in vivo anti-proliferative activity and molecular modeling simulations.

Elsayed RW, Bayoumi SM, El-Subbagh HI, El-Sayed SM. Elsayed RW, et al. Bioorg Med Chem Lett. 2023 May 1;87:129285. doi: 10.1016/j.bmcl.2023.129285. Epub 2023 Apr 11. Bioorg Med Chem Lett. 2023. PMID: 37054758

8

New 2-alkoxycyanopyridine derivatives as inhibitors of EGFR, HER2, and DHFR: Synthesis, anticancer evaluation, and molecular modeling studies.

Hawas SS, El-Sayed SM, Elzahhar PA, Moustafa MA. Hawas SS, et al. Bioorg Chem. 2023 Dec;141:106874. doi: 10.1016/j.bioorg.2023.106874. Epub 2023 Sep 21. Bioorg Chem. 2023. PMID: 37769524

9

Multi-targeted anti-Alzheimer's agents: Synthesis, biological evaluation, and molecular modeling study of some pyrazolopyridine hybrids.

Waly OM, El-Sayed SM, Ghaly MA, El-Subbagh HI. Waly OM, et al. Eur J Med Chem. 2023 Dec 15;262:115880. doi: 10.1016/j.ejmech.2023.115880. Epub 2023 Oct 20. Eur J Med Chem. 2023. PMID: 37871406

10

Synthesis and biological evaluation of O^4'-benzyl-hispidol derivatives and analogs as dual monoamine oxidase-B inhibitors and anti-neuroinflammatory agents.

Hassan AHE, Choi Y, Kim R, Kim HJ, Almatary AM, El-Sayed SM, Lee Y, Lee JK, Park KD, Lee YS. Hassan AHE, et al. Among authors: el sayed sm. Bioorg Med Chem. 2024 Aug 1;110:117826. doi: 10.1016/j.bmc.2024.117826. Epub 2024 Jul 5. Bioorg Med Chem. 2024. PMID: 39004050

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