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Page 1
Conserved epigenetic hallmarks of T cell aging during immunity and malignancy.
Mi T, Soerens AG, Alli S, Kang TG, Vasandan AB, Wang Z, Vezys V, Kimura S, Iacobucci I, Baylin SB, Jones PA, Hiner C, Mueller A, Goldstein H, Mullighan CG, Zebley CC, Masopust D, Youngblood B. Mi T, et al. Among authors: alli s. Nat Aging. 2024 Aug;4(8):1053-1063. doi: 10.1038/s43587-024-00649-5. Epub 2024 Jun 12. Nat Aging. 2024. PMID: 38867059 Free PMC article.
Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes.
Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, Serti E, Turka LA, Busch ME, Stone M, Deeks SG, Sekaly RP, Zehn D, James EA, Nepom GT, Youngblood B. Abdelsamed HA, et al. Among authors: alli s. Nat Immunol. 2020 May;21(5):578-587. doi: 10.1038/s41590-020-0633-5. Epub 2020 Mar 30. Nat Immunol. 2020. PMID: 32231298 Free PMC article.
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity.
Prinzing B, Zebley CC, Petersen CT, Fan Y, Anido AA, Yi Z, Nguyen P, Houke H, Bell M, Haydar D, Brown C, Boi SK, Alli S, Crawford JC, Riberdy JM, Park JJ, Zhou S, Velasquez MP, DeRenzo C, Lazzarotto CR, Tsai SQ, Vogel P, Pruett-Miller SM, Langfitt DM, Gottschalk S, Youngblood B, Krenciute G. Prinzing B, et al. Among authors: alli s. Sci Transl Med. 2021 Nov 17;13(620):eabh0272. doi: 10.1126/scitranslmed.abh0272. Epub 2021 Nov 17. Sci Transl Med. 2021. PMID: 34788079 Free PMC article.
Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation.
Moustaki A, Crawford JC, Alli S, Fan Y, Boi S, Zamora AE, McDonald NMN, Wu G, Nakitandwe J, Newman S, Foy S, Silkov A, Thomas PG, Pappo A, Dyer MA, Stewart E, Federico S, Youngblood B. Moustaki A, et al. Among authors: alli s. Sci Immunol. 2022 Feb 4;7(68):eabf6136. doi: 10.1126/sciimmunol.abf6136. Epub 2022 Feb 4. Sci Immunol. 2022. PMID: 35119937 Free PMC article.
Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy.
Kang TG, Lan X, Mi T, Chen H, Alli S, Lim SE, Bhatara S, Vasandan AB, Ward G, Bentivegna S, Jang J, Spatz ML, Han JH, Schlotmann BC, Jespersen JS, Derenzo C, Vogel P, Yu J, Baylin S, Jones P, O'Connell C, Grønbæk K, Youngblood B, Zebley CC. Kang TG, et al. Among authors: alli s. Science. 2024 Oct 11;386(6718):eadl4492. doi: 10.1126/science.adl4492. Epub 2024 Oct 11. Science. 2024. PMID: 39388542
56 results