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Metabolic inflexibility promotes mitochondrial health during liver regeneration.
Wang X, Menezes CJ, Jia Y, Xiao Y, Venigalla SSK, Cai F, Hsieh MH, Gu W, Du L, Sudderth J, Kim D, Shelton SD, Llamas CB, Lin YH, Zhu M, Merchant S, Bezwada D, Kelekar S, Zacharias LG, Mathews TP, Hoxhaj G, Wynn RM, Tambar UK, DeBerardinis RJ, Zhu H, Mishra P. Wang X, et al. Among authors: zhu h, zhu m. Science. 2024 Jun 14;384(6701):eadj4301. doi: 10.1126/science.adj4301. Epub 2024 Jun 14. Science. 2024. PMID: 38870309 Free PMC article.
Suppression of the SWI/SNF Component Arid1a Promotes Mammalian Regeneration.
Sun X, Chuang JC, Kanchwala M, Wu L, Celen C, Li L, Liang H, Zhang S, Maples T, Nguyen LH, Wang SC, Signer RA, Sorouri M, Nassour I, Liu X, Xu J, Wu M, Zhao Y, Kuo YC, Wang Z, Xing C, Zhu H. Sun X, et al. Among authors: zhu h. Cell Stem Cell. 2016 Apr 7;18(4):456-66. doi: 10.1016/j.stem.2016.03.001. Epub 2016 Mar 24. Cell Stem Cell. 2016. PMID: 27044474 Free PMC article.
Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer.
Sun X, Wang SC, Wei Y, Luo X, Jia Y, Li L, Gopal P, Zhu M, Nassour I, Chuang JC, Maples T, Celen C, Nguyen LH, Wu L, Fu S, Li W, Hui L, Tian F, Ji Y, Zhang S, Sorouri M, Hwang TH, Letzig L, James L, Wang Z, Yopp AC, Singal AG, Zhu H. Sun X, et al. Among authors: zhu h, zhu m. Cancer Cell. 2017 Nov 13;32(5):574-589.e6. doi: 10.1016/j.ccell.2017.10.007. Cancer Cell. 2017. PMID: 29136504 Free PMC article.
The origins and functions of hepatic polyploidy.
Zhang S, Lin YH, Tarlow B, Zhu H. Zhang S, et al. Among authors: zhu h. Cell Cycle. 2019 Jun;18(12):1302-1315. doi: 10.1080/15384101.2019.1618123. Epub 2019 May 26. Cell Cycle. 2019. PMID: 31096847 Free PMC article. Review.
Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.
Lin YH, Zhang S, Zhu M, Lu T, Chen K, Wen Z, Wang S, Xiao G, Luo D, Jia Y, Li L, MacConmara M, Hoshida Y, Singal AG, Yopp A, Wang T, Zhu H. Lin YH, et al. Among authors: zhu h, zhu m. Gastroenterology. 2020 May;158(6):1698-1712.e14. doi: 10.1053/j.gastro.2020.01.026. Epub 2020 Jan 20. Gastroenterology. 2020. PMID: 31972235 Free PMC article.
Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer.
Huang F, Huffman KE, Wang Z, Wang X, Li K, Cai F, Yang C, Cai L, Shih TS, Zacharias LG, Chung A, Yang Q, Chalishazar MD, Ireland AS, Stewart CA, Cargill K, Girard L, Liu Y, Ni M, Xu J, Wu X, Zhu H, Drapkin B, Byers LA, Oliver TG, Gazdar AF, Minna JD, DeBerardinis RJ. Huang F, et al. Among authors: zhu h. J Clin Invest. 2021 Jan 4;131(1):e139929. doi: 10.1172/JCI139929. J Clin Invest. 2021. PMID: 33079728 Free PMC article.
Liver homeostasis is maintained by midlobular zone 2 hepatocytes.
Wei Y, Wang YG, Jia Y, Li L, Yoon J, Zhang S, Wang Z, Zhang Y, Zhu M, Sharma T, Lin YH, Hsieh MH, Albrecht JH, Le PT, Rosen CJ, Wang T, Zhu H. Wei Y, et al. Among authors: zhu h, zhu m. Science. 2021 Feb 26;371(6532):eabb1625. doi: 10.1126/science.abb1625. Science. 2021. PMID: 33632817 Free PMC article.
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