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Autotrophic adaptive laboratory evolution of the acetogen Clostridium autoethanogenum delivers the gas-fermenting strain LAbrini with superior growth, products, and robustness.
Ingelman H, Heffernan JK, Harris A, Brown SD, Shaikh KM, Saqib AY, Pinheiro MJ, de Lima LA, Martinez KR, Gonzalez-Garcia RA, Hawkins G, Daleiden J, Tran L, Zeleznik H, Jensen RO, Reynoso V, Schindel H, Jänes J, Simpson SD, Köpke M, Marcellin E, Valgepea K. Ingelman H, et al. Among authors: marcellin e. N Biotechnol. 2024 Nov 25;83:1-15. doi: 10.1016/j.nbt.2024.06.002. Epub 2024 Jun 11. N Biotechnol. 2024. PMID: 38871051 Free article.
Improved production of propionic acid using genome shuffling.
Luna-Flores CH, Palfreyman RW, Krömer JO, Nielsen LK, Marcellin E. Luna-Flores CH, et al. Among authors: marcellin e. Biotechnol J. 2017 Feb;12(2). doi: 10.1002/biot.201600120. Epub 2016 Oct 20. Biotechnol J. 2017. PMID: 27676587
Maintenance of ATP Homeostasis Triggers Metabolic Shifts in Gas-Fermenting Acetogens.
Valgepea K, de Souza Pinto Lemgruber R, Meaghan K, Palfreyman RW, Abdalla T, Heijstra BD, Behrendorff JB, Tappel R, Köpke M, Simpson SD, Nielsen LK, Marcellin E. Valgepea K, et al. Among authors: marcellin e. Cell Syst. 2017 May 24;4(5):505-515.e5. doi: 10.1016/j.cels.2017.04.008. Epub 2017 May 17. Cell Syst. 2017. PMID: 28527885 Free article.
H2 drives metabolic rearrangements in gas-fermenting Clostridium autoethanogenum.
Valgepea K, de Souza Pinto Lemgruber R, Abdalla T, Binos S, Takemori N, Takemori A, Tanaka Y, Tappel R, Köpke M, Simpson SD, Nielsen LK, Marcellin E. Valgepea K, et al. Among authors: marcellin e. Biotechnol Biofuels. 2018 Mar 1;11:55. doi: 10.1186/s13068-018-1052-9. eCollection 2018. Biotechnol Biofuels. 2018. PMID: 29507607 Free PMC article.
Systems-level engineering and characterisation of Clostridium autoethanogenum through heterologous production of poly-3-hydroxybutyrate (PHB).
de Souza Pinto Lemgruber R, Valgepea K, Tappel R, Behrendorff JB, Palfreyman RW, Plan M, Hodson MP, Simpson SD, Nielsen LK, Köpke M, Marcellin E. de Souza Pinto Lemgruber R, et al. Among authors: marcellin e. Metab Eng. 2019 May;53:14-23. doi: 10.1016/j.ymben.2019.01.003. Epub 2019 Jan 11. Metab Eng. 2019. PMID: 30641139
103 results