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Single nucleotide variation catalog from clinical isolates mapped on tertiary and quaternary structures of ESX-1-related proteins reveals critical regions as putative Mtb therapeutic targets.
Tzfadia O, Gijsbers A, Vujkovic A, Snobre J, Vargas R, Dewaele K, Meehan CJ, Farhat M, Hakke S, Peters PJ, de Jong BC, Siroy A, Ravelli RBG. Tzfadia O, et al. Among authors: farhat m. Microbiol Spectr. 2024 Aug 6;12(8):e0381623. doi: 10.1128/spectrum.03816-23. Epub 2024 Jun 14. Microbiol Spectr. 2024. PMID: 38874407 Free PMC article.
Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues.
Meehan CJ, Goig GA, Kohl TA, Verboven L, Dippenaar A, Ezewudo M, Farhat MR, Guthrie JL, Laukens K, Miotto P, Ofori-Anyinam B, Dreyer V, Supply P, Suresh A, Utpatel C, van Soolingen D, Zhou Y, Ashton PM, Brites D, Cabibbe AM, de Jong BC, de Vos M, Menardo F, Gagneux S, Gao Q, Heupink TH, Liu Q, Loiseau C, Rigouts L, Rodwell TC, Tagliani E, Walker TM, Warren RM, Zhao Y, Zignol M, Schito M, Gardy J, Cirillo DM, Niemann S, Comas I, Van Rie A. Meehan CJ, et al. Among authors: farhat mr. Nat Rev Microbiol. 2019 Sep;17(9):533-545. doi: 10.1038/s41579-019-0214-5. Nat Rev Microbiol. 2019. PMID: 31209399 Review.
Phase variation as a major mechanism of adaptation in Mycobacterium tuberculosis complex.
Vargas R Jr, Luna MJ, Freschi L, Marin M, Froom R, Murphy KC, Campbell EA, Ioerger TR, Sassetti CM, Farhat MR. Vargas R Jr, et al. Among authors: farhat mr. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2301394120. doi: 10.1073/pnas.2301394120. Epub 2023 Jul 3. Proc Natl Acad Sci U S A. 2023. PMID: 37399390 Free PMC article.
408 results