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Page 1
M01 as a novel drug enhancer for specifically targeting the blood-brain barrier.
Breitkreuz-Korff O, Tscheik C, Del Vecchio G, Dithmer S, Walther W, Orthmann A, Wolburg H, Haseloff RF, Schröder L, Blasig IE, Winkler L. Breitkreuz-Korff O, et al. Among authors: dithmer s. J Control Release. 2021 Oct 10;338:137-148. doi: 10.1016/j.jconrel.2021.08.014. Epub 2021 Aug 10. J Control Release. 2021. PMID: 34384796 Free article.
Tight junctions in the blood-brain barrier promote edema formation and infarct size in stroke - Ambivalent effects of sealing proteins.
Winkler L, Blasig R, Breitkreuz-Korff O, Berndt P, Dithmer S, Helms HC, Puchkov D, Devraj K, Kaya M, Qin Z, Liebner S, Wolburg H, Andjelkovic AV, Rex A, Blasig IE, Haseloff RF. Winkler L, et al. Among authors: dithmer s. J Cereb Blood Flow Metab. 2021 Jan;41(1):132-145. doi: 10.1177/0271678X20904687. Epub 2020 Feb 13. J Cereb Blood Flow Metab. 2021. PMID: 32054373 Free PMC article.
Tight junction proteins at the blood-brain barrier: far more than claudin-5.
Berndt P, Winkler L, Cording J, Breitkreuz-Korff O, Rex A, Dithmer S, Rausch V, Blasig R, Richter M, Sporbert A, Wolburg H, Blasig IE, Haseloff RF. Berndt P, et al. Among authors: dithmer s. Cell Mol Life Sci. 2019 May;76(10):1987-2002. doi: 10.1007/s00018-019-03030-7. Epub 2019 Feb 7. Cell Mol Life Sci. 2019. PMID: 30734065 Free PMC article.
Claudin-1-Dependent Destabilization of the Blood-Brain Barrier in Chronic Stroke.
Sladojevic N, Stamatovic SM, Johnson AM, Choi J, Hu A, Dithmer S, Blasig IE, Keep RF, Andjelkovic AV. Sladojevic N, et al. Among authors: dithmer s. J Neurosci. 2019 Jan 23;39(4):743-757. doi: 10.1523/JNEUROSCI.1432-18.2018. Epub 2018 Nov 30. J Neurosci. 2019. PMID: 30504279 Free PMC article.
Trictide, a tricellulin-derived peptide to overcome cellular barriers.
Cording J, Arslan B, Staat C, Dithmer S, Krug SM, Krüger A, Berndt P, Günther R, Winkler L, Blasig IE, Haseloff RF. Cording J, et al. Among authors: dithmer s. Ann N Y Acad Sci. 2017 Oct;1405(1):89-101. doi: 10.1111/nyas.13392. Epub 2017 Jun 20. Ann N Y Acad Sci. 2017. PMID: 28633193
Claudin peptidomimetics modulate tissue barriers for enhanced drug delivery.
Dithmer S, Staat C, Müller C, Ku MC, Pohlmann A, Niendorf T, Gehne N, Fallier-Becker P, Kittel Á, Walter FR, Veszelka S, Deli MA, Blasig R, Haseloff RF, Blasig IE, Winkler L. Dithmer S, et al. Ann N Y Acad Sci. 2017 Jun;1397(1):169-184. doi: 10.1111/nyas.13359. Epub 2017 May 15. Ann N Y Acad Sci. 2017. PMID: 28505395