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14,863 results

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YAP dysregulation triggers hypertrophy by CCN2 secretion and TGFβ uptake in human pluripotent stem cell-derived cardiomyocytes.
Chirikian O, Faynus MA, Merk M, Singh Z, Muray C, Pham J, Chialastri A, Vander Roest A, Goldstein A, Pyle T, Lane KV, Roberts B, Smith JE, Gunawardane RN, Sniadecki NJ, Mack DL, Davis J, Bernstein D, Streichan SJ, Clegg DO, Dey SS, Wilson MZ, Pruitt BL. Chirikian O, et al. Among authors: davis j. bioRxiv [Preprint]. 2024 Jun 5:2024.06.03.597045. doi: 10.1101/2024.06.03.597045. bioRxiv. 2024. PMID: 38895282 Free PMC article. Preprint.
Correcting dilated cardiomyopathy with fibroblast-targeted p38 deficiency.
Bretherton RC, Reichardt IM, Zabrecky KA, Goldstein AJ, Bailey LRJ, Bugg D, McMillen TS, Kooiker KB, Flint GV, Martinson A, Gunaje J, Koser F, Plaster E, Linke WA, Regnier M, Moussavi-Harami F, Sniadecki NJ, DeForest CA, Davis J. Bretherton RC, et al. Among authors: davis j. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.523684. doi: 10.1101/2023.01.23.523684. bioRxiv. 2023. PMID: 36747691 Free PMC article. Preprint.
Danicamtiv increases myosin recruitment and alters the chemomechanical cross bridge cycle in cardiac muscle.
Kooiker KB, Mohran S, Turner KL, Ma W, Flint G, Qi L, Gao C, Zheng Y, McMillen TS, Mandrycky C, Martinson A, Mahoney-Schaefer M, Freeman JC, Costales Arenas EG, Tu AY, Irving TC, Geeves MA, Tanner BCW, Regnier M, Davis J, Moussavi-Harami F. Kooiker KB, et al. Among authors: davis j. bioRxiv [Preprint]. 2023 Feb 3:2023.01.31.526380. doi: 10.1101/2023.01.31.526380. bioRxiv. 2023. Update in: Circ Res. 2023 Aug 18;133(5):430-443. doi: 10.1161/CIRCRESAHA.123.322629 PMID: 36778318 Free PMC article. Updated. Preprint.
MBNL1 regulates programmed postnatal switching between regenerative and differentiated cardiac states.
Bailey LRJ, Bugg D, Reichardt IM, Ortaç CD, Gunaje J, Johnson R, MacCoss MJ, Sakamoto T, Kelly DP, Regnier M, Davis JM. Bailey LRJ, et al. Among authors: davis jm. bioRxiv [Preprint]. 2023 Mar 16:2023.03.16.532974. doi: 10.1101/2023.03.16.532974. bioRxiv. 2023. Update in: Circulation. 2024 Jun 4;149(23):1812-1829. doi: 10.1161/CIRCULATIONAHA.123.066860 PMID: 36993225 Free PMC article. Updated. Preprint.
MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy.
Steczina S, Mohran S, Bailey LRJ, McMillen TS, Kooiker KB, Wood NB, Davis J, Previs MJ, Olivotto I, Pioner JM, Geeves MA, Poggesi C, Regnier M. Steczina S, et al. Among authors: davis j. J Mol Cell Cardiol. 2024 Jun;191:27-39. doi: 10.1016/j.yjmcc.2024.04.010. Epub 2024 Apr 20. J Mol Cell Cardiol. 2024. PMID: 38648963
Higher rates of delay in starting advanced inflammatory bowel disease therapies linked to insurance delays, intravenous infusions, and lack of pharmacy support.
Gottesman S, Xiao K, Nguyen HP, Hernandez E, Saweris E, Jaganathan P, Jafri F, Davis J, Tong K, Tang Z, Gaidos JKJ, Feagins LA. Gottesman S, et al. Among authors: davis j. Clin Transl Gastroenterol. 2024 Dec 24. doi: 10.14309/ctg.0000000000000808. Online ahead of print. Clin Transl Gastroenterol. 2024. PMID: 39718220
Determining the association of hyperoxia while on extracorporeal life support with mortality in neonates following Norwood operation.
Beshish AG, Aljiffry A, Xiang Y, Evans S, Scheel A, Harriott A, Patel S, Amedi A, Harding A, Davis J, Shashidharan S, Kwiatkowski DM. Beshish AG, et al. Among authors: davis j. J Extra Corpor Technol. 2024 Dec;56(4):174-184. doi: 10.1051/ject/2024020. Epub 2024 Dec 20. J Extra Corpor Technol. 2024. PMID: 39705581 Free PMC article.
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