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Page 1
The reparative immunologic consequences of stem cell transplantation as a cellular therapy for refractory Crohn's disease.
Guisado D, Talware S, Wang X, Davis A, Fozilov E, Etra A, Colombel JF, Schaniel C, Tastad C, Levine JE, Ferrara JLM, Chuang LS, Sabic K, Singh S, Marcellino BK, Hoffman R, Cho J, Cohen LJ. Guisado D, et al. Among authors: chuang ls. bioRxiv [Preprint]. 2024 Jun 3:2024.05.30.596699. doi: 10.1101/2024.05.30.596699. bioRxiv. 2024. PMID: 38895305 Free PMC article. Preprint.
Multimodal single-cell analyses reveal mechanisms of perianal fistula in diverse patients with Crohn's disease.
Levantovsky RM, Tastad C, Zhang J, Gettler K, Sabic K, Werner R, Chasteau C, Korie U, Paguay D, Bao M, Han H, Maskey N, Talware S, Patel M, Argmann C, Suarez-Farinas M, Harpaz N, Chuang LS, Cho JH. Levantovsky RM, et al. Among authors: chuang ls. Med. 2024 Aug 9;5(8):886-908.e11. doi: 10.1016/j.medj.2024.03.021. Epub 2024 Apr 24. Med. 2024. PMID: 38663404
Neutralizing Anti-Granulocyte Macrophage-Colony Stimulating Factor Autoantibodies Recognize Post-Translational Glycosylations on Granulocyte Macrophage-Colony Stimulating Factor Years Before Diagnosis and Predict Complicated Crohn's Disease.
Mortha A, Remark R, Del Valle DM, Chuang LS, Chai Z, Alves I, Azevedo C, Gaifem J, Martin J, Petralia F, Tuballes K, Barcessat V, Tai SL, Huang HH, Laface I, Jerez YA, Boschetti G, Villaverde N, Wang MD, Korie UM, Murray J, Choung RS, Sato T, Laird RM, Plevy S, Rahman A, Torres J, Porter C, Riddle MS, Kenigsberg E, Pinho SS, Cho JH, Merad M, Colombel JF, Gnjatic S. Mortha A, et al. Among authors: chuang ls. Gastroenterology. 2022 Sep;163(3):659-670. doi: 10.1053/j.gastro.2022.05.029. Epub 2022 May 24. Gastroenterology. 2022. PMID: 35623454 Free PMC article.
Unravelling the Oral-Gut Axis: Interconnection Between Periodontitis and Inflammatory Bowel Disease, Current Challenges, and Future Perspective.
Tanwar H, Gnanasekaran JM, Allison D, Chuang LS, He X, Aimetti M, Baima G, Costalonga M, Cross RK, Sears C, Mehandru S, Cho J, Colombel JF, Raufman JP, Thumbigere-Math V. Tanwar H, et al. Among authors: chuang ls. J Crohns Colitis. 2024 Aug 14;18(8):1319-1341. doi: 10.1093/ecco-jcc/jjae028. J Crohns Colitis. 2024. PMID: 38417137 Free PMC article. Review.
A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease.
Nayar S, Morrison JK, Giri M, Gettler K, Chuang LS, Walker LA, Ko HM, Kenigsberg E, Kugathasan S, Merad M, Chu J, Cho JH. Nayar S, et al. Among authors: chuang ls. Nature. 2021 May;593(7858):275-281. doi: 10.1038/s41586-021-03484-5. Epub 2021 Mar 31. Nature. 2021. PMID: 33789339 Free PMC article.
Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target.
Chen E, Chuang LS, Giri M, Villaverde N, Hsu NY, Sabic K, Joshowitz S, Gettler K, Nayar S, Chai Z, Alter IL, Chasteau CC, Korie UM, Dzedzik S, Thin TH, Jain A, Moscati A, Bongers G, Duerr RH, Silverberg MS, Brant SR, Rioux JD, Peter I, Schumm LP, Haritunians T, McGovern DP, Itan Y, Cho JH. Chen E, et al. Among authors: chuang ls. Gastroenterology. 2021 Apr;160(5):1709-1724. doi: 10.1053/j.gastro.2020.12.076. Epub 2021 Jan 6. Gastroenterology. 2021. PMID: 33421512 Free PMC article.
Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.
Martin JC, Chang C, Boschetti G, Ungaro R, Giri M, Grout JA, Gettler K, Chuang LS, Nayar S, Greenstein AJ, Dubinsky M, Walker L, Leader A, Fine JS, Whitehurst CE, Mbow ML, Kugathasan S, Denson LA, Hyams JS, Friedman JR, Desai PT, Ko HM, Laface I, Akturk G, Schadt EE, Salmon H, Gnjatic S, Rahman AH, Merad M, Cho JH, Kenigsberg E. Martin JC, et al. Among authors: chuang ls. Cell. 2019 Sep 5;178(6):1493-1508.e20. doi: 10.1016/j.cell.2019.08.008. Epub 2019 Aug 29. Cell. 2019. PMID: 31474370 Free PMC article.
Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets.
Gettler K, Giri M, Kenigsberg E, Martin J, Chuang LS, Hsu NY, Denson LA, Hyams JS, Griffiths A, Noe JD, Crandall WV, Mack DR, Kellermayer R, Abraham C, Hoffman G, Kugathasan S, Cho JH. Gettler K, et al. Among authors: chuang ls. Genes Immun. 2019 Sep;20(7):577-588. doi: 10.1038/s41435-019-0059-y. Epub 2019 Jan 29. Genes Immun. 2019. PMID: 30692607 Free PMC article.
57 results