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Page 1
Structure and repair of replication-coupled DNA breaks.
Pavani R, Tripathi V, Vrtis KB, Zong D, Chari R, Callen E, Pankajam AV, Zhen G, Matos-Rodrigues G, Yang J, Wu S, Reginato G, Wu W, Cejka P, Walter JC, Nussenzweig A. Pavani R, et al. Among authors: reginato g. Science. 2024 Aug 16;385(6710):eado3867. doi: 10.1126/science.ado3867. Epub 2024 Aug 16. Science. 2024. PMID: 38900911 Free PMC article.
A highly specific SpCas9 variant is identified by in vivo screening in yeast.
Casini A, Olivieri M, Petris G, Montagna C, Reginato G, Maule G, Lorenzin F, Prandi D, Romanel A, Demichelis F, Inga A, Cereseto A. Casini A, et al. Among authors: reginato g. Nat Biotechnol. 2018 Mar;36(3):265-271. doi: 10.1038/nbt.4066. Epub 2018 Jan 29. Nat Biotechnol. 2018. PMID: 29431739 Free PMC article.
Rad51 determines pathway usage in post-replication repair.
Meyer D, Ceballos SJ, Gore S, Liu J, Reginato G, Cano-Linares MI, Maslowska KH, Villafañez F, Ede C, Pagès V, Prado F, Cejka P, Heyer WD. Meyer D, et al. Among authors: reginato g. bioRxiv [Preprint]. 2024 Jun 14:2024.06.14.599120. doi: 10.1101/2024.06.14.599120. bioRxiv. 2024. PMID: 38915629 Free PMC article. Preprint.
HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing.
Reginato G, Dello Stritto MR, Wang Y, Hao J, Pavani R, Schmitz M, Halder S, Morin V, Cannavo E, Ceppi I, Braunshier S, Acharya A, Ropars V, Charbonnier JB, Jinek M, Nussenzweig A, Ha T, Cejka P. Reginato G, et al. Nat Commun. 2024 Jul 10;15(1):5789. doi: 10.1038/s41467-024-50080-y. Nat Commun. 2024. PMID: 38987539 Free PMC article.
Mechanism of BRCA1-BARD1 function in DNA end resection and DNA protection.
Ceppi I, Dello Stritto MR, Mütze M, Braunshier S, Mengoli V, Reginato G, Võ HMP, Jimeno S, Acharya A, Roy M, Sanchez A, Halder S, Howard SM, Guérois R, Huertas P, Noordermeer SM, Seidel R, Cejka P. Ceppi I, et al. Among authors: reginato g. Nature. 2024 Oct;634(8033):492-500. doi: 10.1038/s41586-024-07909-9. Epub 2024 Sep 11. Nature. 2024. PMID: 39261728 Free PMC article.
Mre11-Rad50 oligomerization promotes DNA double-strand break repair.
Kissling VM, Reginato G, Bianco E, Kasaciunaite K, Tilma J, Cereghetti G, Schindler N, Lee SS, Guérois R, Luke B, Seidel R, Cejka P, Peter M. Kissling VM, et al. Among authors: reginato g. Nat Commun. 2022 May 2;13(1):2374. doi: 10.1038/s41467-022-29841-0. Nat Commun. 2022. PMID: 35501303 Free PMC article.
71 results