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Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues.
Sala AJ, Grant RA, Imran G, Morton C, Brielmann RM, Bott LC, Watts J, Morimoto RI. Sala AJ, et al. Among authors: morimoto ri. bioRxiv [Preprint]. 2023 Apr 25:2023.04.25.537803. doi: 10.1101/2023.04.25.537803. bioRxiv. 2023. Update in: Genes Dev. 2024 Jun 25;38(9-10):380-392. doi: 10.1101/gad.351829.124 PMID: 37162952 Free PMC article. Updated. Preprint.
A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway.
Elsasser S, Elia LP, Morimoto RI, Powers ET, Finley D, Costa B, Budron M, Tokuno Z, Wang S, Iyer RG, Barth B, Mockler E, Finkbeiner S, Gestwicki JE, Richardson RAK, Stoeger T, Tan EP, Xiao Q, Cole CM, Massey LA, Garza D, Kelly JW, Rainbolt TK, Chou CC, Masto VB, Frydman J, Nixon RA. Elsasser S, et al. Among authors: morimoto ri. bioRxiv [Preprint]. 2023 Mar 24:2023.03.22.533675. doi: 10.1101/2023.03.22.533675. bioRxiv. 2023. PMID: 36993380 Free PMC article. Preprint.
HaloTag as a substrate-based macroautophagy reporter.
Xiao Q, Cruz G, Botham R, Fox SG, Yu A, Allen S, Morimoto RI, Kelly JW. Xiao Q, et al. Among authors: morimoto ri. Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2322500121. doi: 10.1073/pnas.2322500121. Epub 2024 Jul 29. Proc Natl Acad Sci U S A. 2024. PMID: 39074281
Aging is associated with a systemic length-associated transcriptome imbalance.
Stoeger T, Grant RA, McQuattie-Pimentel AC, Anekalla KR, Liu SS, Tejedor-Navarro H, Singer BD, Abdala-Valencia H, Schwake M, Tetreault MP, Perlman H, Balch WE, Chandel NS, Ridge KM, Sznajder JI, Morimoto RI, Misharin AV, Budinger GRS, Nunes Amaral LA. Stoeger T, et al. Among authors: morimoto ri. Nat Aging. 2022 Dec;2(12):1191-1206. doi: 10.1038/s43587-022-00317-6. Epub 2022 Dec 9. Nat Aging. 2022. PMID: 37118543 Free PMC article.
Individual target pharmacokinetic/pharmacodynamic attainment rates among meropenem-treated patients admitted to the ICU with hospital-acquired pneumonia.
Rohani R, Scheetz MH, Donnelly HK, Donayre A, Kang M, Diaz E, Dedicatoria K, Hauser AR, Ozer EA, Nozick S, Qi C, Pawlowski AE, Neely MN, Misharin AV, Wunderink RG, Rhodes NJ; NU SCRIPT Study investigators. Rohani R, et al. J Antimicrob Chemother. 2022 Oct 28;77(11):2956-2959. doi: 10.1093/jac/dkac245. J Antimicrob Chemother. 2022. PMID: 35869779 Free PMC article.
Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons.
Capano LS, Sato C, Ficulle E, Yu A, Horie K, Kwon JS, Burbach KF, Barthélemy NR, Fox SG, Karch CM, Bateman RJ, Houlden H, Morimoto RI, Holtzman DM, Duff KE, Yoo AS. Capano LS, et al. Among authors: morimoto ri. Cell Stem Cell. 2022 Jun 2;29(6):918-932.e8. doi: 10.1016/j.stem.2022.04.018. Cell Stem Cell. 2022. PMID: 35659876 Free PMC article.
261 results