O'Shea TM - Search Results

1

Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice.

O'Shea TM, Ao Y, Wang S, Ren Y, Cheng AL, Kawaguchi R, Shi Z, Swarup V, Sofroniew MV. O'Shea TM, et al. Nat Neurosci. 2024 Aug;27(8):1505-1521. doi: 10.1038/s41593-024-01684-6. Epub 2024 Jun 21. Nat Neurosci. 2024. PMID: 38907165 Free PMC article.

2

Astrocyte scar formation aids central nervous system axon regeneration.

Anderson MA, Burda JE, Ren Y, Ao Y, O'Shea TM, Kawaguchi R, Coppola G, Khakh BS, Deming TJ, Sofroniew MV. Anderson MA, et al. Nature. 2016 Apr 14;532(7598):195-200. doi: 10.1038/nature17623. Epub 2016 Mar 30. Nature. 2016. PMID: 27027288 Free PMC article.

3

Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury.

Ren Y, Ao Y, O'Shea TM, Burda JE, Bernstein AM, Brumm AJ, Muthusamy N, Ghashghaei HT, Carmichael ST, Cheng L, Sofroniew MV. Ren Y, et al. Sci Rep. 2017 Jan 24;7:41122. doi: 10.1038/srep41122. Sci Rep. 2017. PMID: 28117356 Free PMC article.

4

Cell biology of spinal cord injury and repair.

O'Shea TM, Burda JE, Sofroniew MV. O'Shea TM, et al. J Clin Invest. 2017 Sep 1;127(9):3259-3270. doi: 10.1172/JCI90608. Epub 2017 Jul 24. J Clin Invest. 2017. PMID: 28737515 Free PMC article. Review.

5

Conformation-Directed Formation of Self-Healing Diblock Copolypeptide Hydrogels via Polyion Complexation.

Sun Y, Wollenberg AL, O'Shea TM, Cui Y, Zhou ZH, Sofroniew MV, Deming TJ. Sun Y, et al. J Am Chem Soc. 2017 Oct 25;139(42):15114-15121. doi: 10.1021/jacs.7b08190. Epub 2017 Oct 12. J Am Chem Soc. 2017. PMID: 28976744 Free PMC article.

6

Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery.

Wollenberg AL, O'Shea TM, Kim JH, Czechanski A, Reinholdt LG, Sofroniew MV, Deming TJ. Wollenberg AL, et al. Biomaterials. 2018 Sep;178:527-545. doi: 10.1016/j.biomaterials.2018.03.057. Epub 2018 Apr 5. Biomaterials. 2018. PMID: 29657091 Free PMC article.

7

Required growth facilitators propel axon regeneration across complete spinal cord injury.

Anderson MA, O'Shea TM, Burda JE, Ao Y, Barlatey SL, Bernstein AM, Kim JH, James ND, Rogers A, Kato B, Wollenberg AL, Kawaguchi R, Coppola G, Wang C, Deming TJ, He Z, Courtine G, Sofroniew MV. Anderson MA, et al. Nature. 2018 Sep;561(7723):396-400. doi: 10.1038/s41586-018-0467-6. Epub 2018 Aug 29. Nature. 2018. PMID: 30158698 Free PMC article.

8

Injectable diblock copolypeptide hydrogel provides platform to deliver effective concentrations of paclitaxel to an intracranial xenograft model of glioblastoma.

Garrett MC, O'Shea TM, Wollenberg AL, Bernstein AM, Hung D, Staarman B, Soto H, Deming TJ, Sofroniew MV, Kornblum HI. Garrett MC, et al. PLoS One. 2020 Jul 24;15(7):e0219632. doi: 10.1371/journal.pone.0219632. eCollection 2020. PLoS One. 2020. PMID: 32706829 Free PMC article.

9

Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions.

OʼShea TM, Wollenberg AL, Kim JH, Ao Y, Deming TJ, Sofroniew MV. OʼShea TM, et al. Nat Commun. 2020 Dec 4;11(1):6203. doi: 10.1038/s41467-020-19906-3. Nat Commun. 2020. PMID: 33277474 Free PMC article.

10

Divergent transcriptional regulation of astrocyte reactivity across disorders.

Burda JE, O'Shea TM, Ao Y, Suresh KB, Wang S, Bernstein AM, Chandra A, Deverasetty S, Kawaguchi R, Kim JH, McCallum S, Rogers A, Wahane S, Sofroniew MV. Burda JE, et al. Nature. 2022 Jun;606(7914):557-564. doi: 10.1038/s41586-022-04739-5. Epub 2022 May 25. Nature. 2022. PMID: 35614216 Free PMC article.

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