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NOD2 activation enhances macrophage Fcγ receptor function and may increase the efficacy of antibody therapy.
Merchand-Reyes G, Bull MF, Santhanam R, Valencia-Pena ML, Murugesan RA, Chordia A, Mo XM, Robledo-Avila FH, Ruiz-Rosado JD, Carson WE 3rd, Byrd JC, Woyach JA, Tridandapani S, Butchar JP. Merchand-Reyes G, et al. Among authors: santhanam r. Front Immunol. 2024 Jun 11;15:1409333. doi: 10.3389/fimmu.2024.1409333. eCollection 2024. Front Immunol. 2024. PMID: 38919608 Free PMC article.
Activation of the Intracellular Pattern Recognition Receptor NOD2 Promotes Acute Myeloid Leukemia (AML) Cell Apoptosis and Provides a Survival Advantage in an Animal Model of AML.
Buteyn NJ, Santhanam R, Merchand-Reyes G, Murugesan RA, Dettorre GM, Byrd JC, Sarkar A, Vasu S, Mundy-Bosse BL, Butchar JP, Tridandapani S. Buteyn NJ, et al. Among authors: santhanam r. J Immunol. 2020 Apr 1;204(7):1988-1997. doi: 10.4049/jimmunol.1900885. Epub 2020 Feb 24. J Immunol. 2020. PMID: 32094205 Free PMC article.
Interferon-γ Promotes Antibody-mediated Fratricide of Acute Myeloid Leukemia Cells.
Fatehchand K, McMichael EL, Reader BF, Fang H, Santhanam R, Gautam S, Elavazhagan S, Mehta P, Buteyn NJ, Merchand-Reyes G, Vasu S, Mo X, Benson DM Jr, Blachly JS, Carson WE 3rd, Byrd JC, Butchar JP, Tridandapani S. Fatehchand K, et al. Among authors: santhanam r. J Biol Chem. 2016 Dec 2;291(49):25656-25666. doi: 10.1074/jbc.M116.753145. Epub 2016 Oct 25. J Biol Chem. 2016. PMID: 27780867 Free PMC article.
Anti-leukemic effects of all-trans retinoic acid in combination with Daratumumab in acute myeloid leukemia.
Buteyn NJ, Fatehchand K, Santhanam R, Fang H, Dettorre GM, Gautam S, Harrington BK, Henderson SE, Merchand-Reyes G, Mo X, Benson DM, Carson WE 3rd, Vasu S, Byrd JC, Butchar JP, Tridandapani S. Buteyn NJ, et al. Among authors: santhanam r. Int Immunol. 2018 Jul 24;30(8):375-383. doi: 10.1093/intimm/dxy040. Int Immunol. 2018. PMID: 29868798 Free PMC article.
Activation of plasmacytoid dendritic cells promotes AML-cell fratricide.
Fatehchand K, Mehta P, Colvin CB, Buteyn NJ, Santhanam R, Merchand-Reyes G, Inshaar H, Shen B, Mo X, Mundy-Bosse B, Tridandapani S, Butchar JP. Fatehchand K, et al. Among authors: santhanam r. Oncotarget. 2021 Apr 27;12(9):878-890. doi: 10.18632/oncotarget.27949. eCollection 2021 Apr 27. Oncotarget. 2021. PMID: 33953842 Free PMC article.
130 results