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PI3KCA mutations and/or PTEN loss in Her2-positive breast carcinomas treated with trastuzumab are not related to resistance to anti-Her2 therapy.
Barbareschi M, Cuorvo LV, Girlando S, Bragantini E, Eccher C, Leonardi E, Ferro A, Caldara A, Triolo R, Cantaloni C, Decarli N, Galligioni E, Dalla Palma P. Barbareschi M, et al. Among authors: caldara a. Virchows Arch. 2012 Aug;461(2):129-39. doi: 10.1007/s00428-012-1267-2. Epub 2012 Jun 29. Virchows Arch. 2012. PMID: 22744290
Whole Breast Irradiation Versus Intraoperative Electron Radiation Therapy for Breast Conserving Therapy: A Large Mature Single Institution Matched-Pair Evaluation of True Local Relapse, Progression Free Survival, and Overall Survival.
De Rose F, Mussari S, Di Brina L, Ravanelli D, Ziglio F, Menegotti L, Ferro A, Caldara A, Berlanda G, Gasperetti F, Magri E, Bandera L, Ferrazza P, Fersino S, Andolina M, Martignano A, Delana A, Bou Selman S, Vanoni V. De Rose F, et al. Among authors: caldara a. Int J Radiat Oncol Biol Phys. 2023 Jul 15;116(4):757-769. doi: 10.1016/j.ijrobp.2023.01.049. Epub 2023 Feb 1. Int J Radiat Oncol Biol Phys. 2023. PMID: 36736632
PI3KCA mutation status is of limited prognostic relevance in ER-positive breast cancer patients treated with hormone therapy.
Cuorvo LV, Verderio P, Ciniselli CM, Girlando S, Decarli N, Leonardi E, Ferro A, Caldara A, Triolo R, Eccher C, Cantaloni C, Mauri F, Seckl M, Volante M, Buttitta F, Marchetti A, Silvia Q, Galligioni E, Palma PD, Barbareschi M. Cuorvo LV, et al. Among authors: caldara a. Virchows Arch. 2014 Jan;464(1):85-93. doi: 10.1007/s00428-013-1500-7. Virchows Arch. 2014. PMID: 24233241
Real-world ANASTASE study of atezolizumab+nab-paclitaxel as first-line treatment of PD-L1-positive metastatic triple-negative breast cancer.
Fabi A, Carbognin L, Botticelli A, Paris I, Fuso P, Savastano MC, La Verde N, Strina C, Pedersini R, Guarino S, Curigliano G, Criscitiello C, Raffaele M, Beano A, Franco A, Valerio MR, Verderame F, Fontana A, Haspinger ER, Caldara A, Di Leone A, Tortora G, Giannarelli D, Scambia G. Fabi A, et al. Among authors: caldara a. NPJ Breast Cancer. 2023 Sep 8;9(1):73. doi: 10.1038/s41523-023-00579-2. NPJ Breast Cancer. 2023. PMID: 37684252 Free PMC article.
Phase II study of eribulin in combination with gemcitabine for the treatment of patients with locally advanced or metastatic triple negative breast cancer (ERIGE trial). Clinical and pharmacogenetic results on behalf of the Gruppo Oncologico Italiano di Ricerca Clinica (GOIRC).
Pellegrino B, Cavanna L, Boggiani D, Zamagni C, Frassoldati A, Schirone A, Caldara A, Rocca A, Gori S, Piacentini F, Berardi R, Brandes AA, Foglietta J, Villa F, Todeschini R, Tognetto M, Naldi N, Bortesi B, Montemurro F, Ardizzoni A, Boni L, Musolino A. Pellegrino B, et al. Among authors: caldara a. ESMO Open. 2021 Feb;6(1):100019. doi: 10.1016/j.esmoop.2020.100019. Epub 2020 Dec 31. ESMO Open. 2021. PMID: 33399082 Free PMC article. Clinical Trial.
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