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Safety, tolerability, pharmacokinetics, and pharmacodynamics of a soluble guanylate cyclase stimulator, HEC95468, in healthy volunteers: a randomized, double-blinded, placebo-controlled phase 1 trial.
Gui YZ, Wang W, Wu QQ, Ding QC, Qian HJ, Lu QB, Zhang YJ, Zhuang YL, Deng L, Zuo YL, Luo L, Jia JY. Gui YZ, et al. Among authors: qian hj. Front Pharmacol. 2024 Jun 12;15:1359939. doi: 10.3389/fphar.2024.1359939. eCollection 2024. Front Pharmacol. 2024. PMID: 38933676 Free PMC article.
A phase 1 randomized study compare the pharmacokinetics, safety and immunogenicity of HLX04 to reference bevacizumab sourced from the United States, the European Union, and China in healthy Chinese male volunteers.
Zhu X, Qian H, Sun J, Wu M, Yu C, Ding Y, Zhang X, Chai K, Li X. Zhu X, et al. Cancer Chemother Pharmacol. 2021 Sep;88(3):465-474. doi: 10.1007/s00280-021-04297-z. Epub 2021 Jun 4. Cancer Chemother Pharmacol. 2021. PMID: 34086067 Free PMC article. Clinical Trial.
Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects.
Qian HJ, Wang Y, Zhang MQ, Xie YC, Wu QQ, Liang LY, Cao Y, Duan HQ, Tian GH, Ma J, Zhang ZB, Li N, Jia JY, Zhang J, Aisa HA, Shen JS, Yu C, Jiang HL, Zhang WH, Wang Z, Liu GY. Qian HJ, et al. Acta Pharmacol Sin. 2022 Dec;43(12):3130-3138. doi: 10.1038/s41401-022-00895-6. Epub 2022 Mar 16. Acta Pharmacol Sin. 2022. PMID: 35296780 Free PMC article.
104 results